biostudies-literatureUnknown96Althaus T<h4>Objectives</h4>This study investigated causes of fever in the primary levels of care in Southeast Asia, and evaluated whether C-reactive protein (CRP) could distinguish bacterial from viral pathogens.<h4>Methods</h4>Blood and nasopharyngeal swab specimens were taken from children and adults with fever (>37.5 °C) or history of fever (<14 days) in Thailand and Myanmar.<h4>Results</h4>Of 773 patients with at least one blood or nasopharyngeal swab specimen collected, 227 (29.4%) had a target organism detected. Influenza virus type A was detected in 85/227 cases (37.5%), followed by dengue virus (30 cases, 13.2%), respiratory syncytial virus (24 cases, 10.6%) and Leptospira spp. (nine cases, 4.0%). Clinical outcomes were similar between patients with a bacterial or a viral organism, regardlInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases334-342https://www.ebi.ac.uk/biostudies/studies/S-EPMC7211754biostudies-literatureCauses of fever in primary care in Southeast Asia and the performance of C-reactive protein in discriminating bacterial from viral pathogens.PMC7211754Smit PWDay NPJAlthaus TWinchell JMPeerawaranun PBlacksell SLubell YThaipadungpanit JDittrich SSmithuis FSwe MMMTurner PGreer RCDiaz MHWangrangsimakul TfalseCauses of fever in primary care in Southeast Asia and the performance of C-reactive protein in discriminating bacterial from viral pathogens.<h4>Objectives</h4>This study investigated causes of fever in the primary levels of care in Southeast Asia, and evaluated whether C-reactive protein (CRP) could distinguish bacterial from viral pathogens.<h4>Methods</h4>Blood and nasopharyngeal swab specimens were taken from children and adults with fever (>37.5 °C) or history of fever (<14 days) in Thailand and Myanmar.<h4>Results</h4>Of 773 patients with at least one blood or nasopharyngeal swab specimen collected, 227 (29.4%) had a target organism detected. Influenza virus type A was detected in 85/227 cases (37.5%), followed by dengue virus (30 cases, 13.2%), respiratory syncytial virus (24 cases, 10.6%) and Leptospira spp. (nine cases, 4.0%). Clinical outcomes were similar between patients with a bacterial or a viral organism, regardl2020-01-01T00:00:00Z2020 Jul2026-05-04T00:06:06.785Z2020-05-26T07:00:21ZS-EPMC72117543243793710.1016/j.ijid.2020.05.016