{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Umuhire Juru A"],"funding":["National Institute of Allergy and Infectious Diseases","Division of Chemistry","Duke University","NIAID NIH HHS","Prostate Cancer Foundation"],"pagination":["3555-3558"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7218690"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["56(24)"],"pubmed_abstract":["This study establishes the applicability of imine-based dynamic combinatorial chemistry to discover non-covalent ligands for RNA targets. We elucidate properties underlying the reactivity of arylamines and demonstrate target-guided amplification of tight binders in an amiloride-based dynamic library."],"journal":["Chemical communications (Cambridge, England)"],"pubmed_title":["Template-guided selection of RNA ligands using imine-based dynamic combinatorial chemistry."],"pmcid":["PMC7218690"],"funding_grant_id":["Young Investigator Award","U54 AI150470","CAREER 1750375"],"pubmed_authors":["Umuhire Juru A","Cai Z","Jan A","Hargrove AE"],"additional_accession":[]},"is_claimable":false,"name":"Template-guided selection of RNA ligands using imine-based dynamic combinatorial chemistry.","description":"This study establishes the applicability of imine-based dynamic combinatorial chemistry to discover non-covalent ligands for RNA targets. We elucidate properties underlying the reactivity of arylamines and demonstrate target-guided amplification of tight binders in an amiloride-based dynamic library.","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Mar","modification":"2025-04-04T23:51:23.969Z","creation":"2025-04-04T23:51:23.969Z"},"accession":"S-EPMC7218690","cross_references":{"pubmed":["32104839"],"doi":["10.1039/d0cc00266f"]}}