biostudies-literatureUnknown55(4)Ryan ALInfluenza vaccination is recommended for children following allogeneic haematopoietic stem cell transplant (HSCT), however there is limited evidence regarding its benefit. A prospective multicentre study was conducted to evaluate the immunogenicity of the inactivated influenza vaccine in children who have undergone HSCT compared with healthy age-matched controls. Participants were vaccinated between 2013 and 2016 according to Australian guidelines. Influenza-specific hemagglutinin inhibition antibody titres were performed prior to each vaccination and 4 weeks following the final vaccination. A nasopharyngeal aspirate for influenza was performed on participants that developed influenza-like illness. There were 86 children recruited; 43 who had undergone HSCT and 43 controls. For the HSCT grBone marrow transplantation773-779https://www.ebi.ac.uk/biostudies/studies/S-EPMC7223911biostudies-literatureImmunogenicity of the inactivated influenza vaccine in children who have undergone allogeneic haematopoietic stem cell transplant.PMC7223911Kerr FRichmond PCCarolan LABarr IGWadia UDBlyth CCJacoby PLaurie KLFraser CMechinaud FCheung LCRyan ALTapp HKotecha RSGottardo NGfalseImmunogenicity of the inactivated influenza vaccine in children who have undergone allogeneic haematopoietic stem cell transplant.Influenza vaccination is recommended for children following allogeneic haematopoietic stem cell transplant (HSCT), however there is limited evidence regarding its benefit. A prospective multicentre study was conducted to evaluate the immunogenicity of the inactivated influenza vaccine in children who have undergone HSCT compared with healthy age-matched controls. Participants were vaccinated between 2013 and 2016 according to Australian guidelines. Influenza-specific hemagglutinin inhibition antibody titres were performed prior to each vaccination and 4 weeks following the final vaccination. A nasopharyngeal aspirate for influenza was performed on participants that developed influenza-like illness. There were 86 children recruited; 43 who had undergone HSCT and 43 controls. For the HSCT gr2020-01-01T00:00:00Z2020 Apr2025-04-19T01:47:15.332Z2020-05-22T20:14:53ZS-EPMC72239113165923610.1038/s41409-019-0728-5