biostudies-literatureUnknown227Dehghani PThe novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), that causes coronavirus disease 2019 (COVID-19), has resulted in a global pandemic. Patients with cardiovascular risk factors or established cardiovascular disease are more likely to experience severe or critical COVID-19 illness and myocardial injury is a key extra-pulmonary manifestation. These patients frequently present with ST-elevation on an electrocardiogram (ECG) due to multiple etiologies including obstructive, non-obstructive, and/or angiographically normal coronary arteries. The incidence of ST-elevation myocardial infarction (STEMI) mimics in COVID-19-positive hospitalized patients, and the association with morbidity and mortality is unknown. Understanding the natural history and appropriate maAmerican heart journal11-18https://www.ebi.ac.uk/biostudies/studies/S-EPMC7229476biostudies-literature<i>N</i>orth <i>A</i>merican <i>C</i>OVID-19 ST-Segment-Elevation <i>M</i>yocardial <i>I</i>nfarction (NACMI) registry: Rationale, design, and implications.PMC7229476Wood DAGrines CLDehghani PSchmidt CHenry TDGiri JMahmud EGarcia SBagai AGarberich RSaw JSharkey SKaul PDavidson LJWelt FGShah BNayak KLy HQMeraj Pfalse<i>N</i>orth <i>A</i>merican <i>C</i>OVID-19 ST-Segment-Elevation <i>M</i>yocardial <i>I</i>nfarction (NACMI) registry: Rationale, design, and implications.The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), that causes coronavirus disease 2019 (COVID-19), has resulted in a global pandemic. Patients with cardiovascular risk factors or established cardiovascular disease are more likely to experience severe or critical COVID-19 illness and myocardial injury is a key extra-pulmonary manifestation. These patients frequently present with ST-elevation on an electrocardiogram (ECG) due to multiple etiologies including obstructive, non-obstructive, and/or angiographically normal coronary arteries. The incidence of ST-elevation myocardial infarction (STEMI) mimics in COVID-19-positive hospitalized patients, and the association with morbidity and mortality is unknown. Understanding the natural history and appropriate ma2020-01-01T00:00:00Z2020 Sep2026-06-03T01:52:03.918Z2020-08-29T07:19:02ZS-EPMC72294763242519810.1016/j.ahj.2020.05.006