{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["11"],"submitter":["Shen L"],"pubmed_abstract":["Six previously undescribed ophiobolin-type sesterterpenes, namely, bipolatoxins A-F (<b>1</b>-<b>6</b>); and one previously undescribed pimarane-type diterpene, namely, 1β-hydroxy momilactone A (<b>7</b>); together with three known compounds, namely, 25-hydroxyophiobolin I (<b>8</b>), ophiobolin I (<b>9</b>), and ophiobolin A lactone (<b>10</b>); were isolated and identified from the endophytic fungus <i>Bipolaris</i> species TJ403-B1. Their structures with absolute configurations were elucidated on the basis of extensive spectroscopic analyses (including 1D and 2D nuclear magnetic resonance (NMR) and high-resolution electrospray ionization mass spectroscopy data), single-crystal X-ray diffraction analyses, and comparison of experimental circular dichroism data. All compounds (except for <"],"journal":["Frontiers in microbiology"],"pagination":["856"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7273749"],"repository":["biostudies-literature"],"pubmed_title":["Novel Antimicrobial Compounds as Ophiobolin-Type Sesterterpenes and Pimarane-Type Diterpene From <i>Bipolaris</i> Species TJ403-B1."],"pmcid":["PMC7273749"],"pubmed_authors":["Shen L","Li H","He Y","Lin S","Liu M","Hu Z","Zhang Y","Chai C","Al Anbari WH","Wang J"],"additional_accession":[]},"is_claimable":false,"name":"Novel Antimicrobial Compounds as Ophiobolin-Type Sesterterpenes and Pimarane-Type Diterpene From <i>Bipolaris</i> Species TJ403-B1.","description":"Six previously undescribed ophiobolin-type sesterterpenes, namely, bipolatoxins A-F (<b>1</b>-<b>6</b>); and one previously undescribed pimarane-type diterpene, namely, 1β-hydroxy momilactone A (<b>7</b>); together with three known compounds, namely, 25-hydroxyophiobolin I (<b>8</b>), ophiobolin I (<b>9</b>), and ophiobolin A lactone (<b>10</b>); were isolated and identified from the endophytic fungus <i>Bipolaris</i> species TJ403-B1. Their structures with absolute configurations were elucidated on the basis of extensive spectroscopic analyses (including 1D and 2D nuclear magnetic resonance (NMR) and high-resolution electrospray ionization mass spectroscopy data), single-crystal X-ray diffraction analyses, and comparison of experimental circular dichroism data. All compounds (except for <","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020","modification":"2026-04-30T22:53:28.248Z","creation":"2020-06-20T07:04:54Z"},"accession":"S-EPMC7273749","cross_references":{"pubmed":["32547498"],"doi":["10.3389/fmicb.2020.00856"]}}