biostudies-literatureUnknown109(8)Ludvigsson JFRegion Örebro länKarolinska Institutet<h4>Aim</h4>Many countries have closed schools and kindergartens to minimise COVID-19, but the role that children play in disease transmission is unclear.<h4>Methods</h4>A systematic literature review of the MEDLINE and EMBASE databases and medRxiv/bioRxiv preprint servers to 11 May 2020 identified published and unpublished papers on COVID-19 transmission by children.<h4>Results</h4>We identified 700 scientific papers and letters and 47 full texts were studied in detail. Children accounted for a small fraction of COVID-19 cases and mostly had social contacts with peers or parents, rather than older people at risk of severe disease. Data on viral loads were scarce, but indicated that children may have lower levels than adults, partly because they often have fewer symptoms, and this should dActa paediatrica (Oslo, Norway : 1992)1525-1530https://www.ebi.ac.uk/biostudies/studies/S-EPMC7280674biostudies-literatureChildren are unlikely to be the main drivers of the COVID-19 pandemic - A systematic review.PMC7280674Ludvigsson JFfalseChildren are unlikely to be the main drivers of the COVID-19 pandemic - A systematic review.<h4>Aim</h4>Many countries have closed schools and kindergartens to minimise COVID-19, but the role that children play in disease transmission is unclear.<h4>Methods</h4>A systematic literature review of the MEDLINE and EMBASE databases and medRxiv/bioRxiv preprint servers to 11 May 2020 identified published and unpublished papers on COVID-19 transmission by children.<h4>Results</h4>We identified 700 scientific papers and letters and 47 full texts were studied in detail. Children accounted for a small fraction of COVID-19 cases and mostly had social contacts with peers or parents, rather than older people at risk of severe disease. Data on viral loads were scarce, but indicated that children may have lower levels than adults, partly because they often have fewer symptoms, and this should d2020-01-01T00:00:00Z2020 Aug2026-05-07T07:37:27.642Z2022-07-19T09:33:09.945ZS-EPMC72806743243096410.1111/apa.15371