{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9(5)"],"submitter":["Hartrampf PE"],"pubmed_abstract":["(1) Background: Prostate-specific membrane antigen (PSMA)-derived tumour volume (PSMA-TV) and total lesion PSMA (TL-PSMA) from PSMA PET/CT scans are promising biomarkers for assessing treatment response in prostate cancer (PCa). Currently, it is unclear whether different software tools for assessing PSMA-TV and TL-PSMA produce comparable results. (2) Methods: 68Ga-PSMA PET/CT scans from n = 21 patients with castration-resistant PCa (CRPC) receiving chemotherapy were identified from our single-centre database. PSMA-TV and TL-PSMA were calculated with Syngo.via (Siemens) as well as the freely available Beth Israel plugin for FIJI (Fiji Is Just ImageJ) before and after chemotherapy. While statistical comparability was illustrated and quantified via Bland-Altman diagrams, the clinical agreemen"],"journal":["Journal of clinical medicine"],"pagination":["E1390"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7290891"],"repository":["biostudies-literature"],"pubmed_title":["Metabolic Tumour Volume from PSMA PET/CT Scans of Prostate Cancer Patients during Chemotherapy-Do Different Software Solutions Deliver Comparable Results?"],"pmcid":["PMC7290891"],"pubmed_authors":["Brumberg J","Lapa C","Seitz AK","Heinrich M","Kubler H","Schirbel A","Krebs M","Buck AK","Hartrampf PE","Sokolakis I","Kalogirou C"],"additional_accession":[]},"is_claimable":false,"name":"Metabolic Tumour Volume from PSMA PET/CT Scans of Prostate Cancer Patients during Chemotherapy-Do Different Software Solutions Deliver Comparable Results?","description":"(1) Background: Prostate-specific membrane antigen (PSMA)-derived tumour volume (PSMA-TV) and total lesion PSMA (TL-PSMA) from PSMA PET/CT scans are promising biomarkers for assessing treatment response in prostate cancer (PCa). Currently, it is unclear whether different software tools for assessing PSMA-TV and TL-PSMA produce comparable results. (2) Methods: 68Ga-PSMA PET/CT scans from n = 21 patients with castration-resistant PCa (CRPC) receiving chemotherapy were identified from our single-centre database. PSMA-TV and TL-PSMA were calculated with Syngo.via (Siemens) as well as the freely available Beth Israel plugin for FIJI (Fiji Is Just ImageJ) before and after chemotherapy. While statistical comparability was illustrated and quantified via Bland-Altman diagrams, the clinical agreemen","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 May","modification":"2025-04-04T08:48:26.188Z","creation":"2020-06-22T07:03:21Z"},"accession":"S-EPMC7290891","cross_references":{"pubmed":["32397223"],"doi":["10.3390/jcm9051390"]}}