{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Murea M"],"funding":["NIA NIH HHS","National Institute on Aging"],"pagination":["86"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7298797"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["6"],"pubmed_abstract":["Background
Although older adults encompass almost half of patients with advanced chronic kidney disease, it remains unclear which long-term hemodialysis vascular access type, arteriovenous fistula or arteriovenous graft, is optimal with respect to effectiveness and patient satisfaction. Clinical outcomes based on the initial AV access type have not been evaluated in randomized controlled trials. This pilot study tested the feasibility of randomizing older adults with advanced kidney disease to initial arteriovenous fistula versus graft vascular access surgery.Methods
Patients 65 years or older with pre-dialysis chronic kidney disease or incident end-stage kidney disease and no prior arteriovenous vascular access intervention were randomized in a 1:1 ratio to undergo surgica"],"journal":["Pilot and feasibility studies"],"pubmed_title":["A randomized pilot study to evaluate graft versus fistula vascular access strategy in older patients with advanced kidney disease: results of a feasibility study."],"pmcid":["PMC7298797"],"funding_grant_id":["R03AG060178-01","R03 AG060178"],"pubmed_authors":["Divers J","Edwards MS","Tuttle AB","Moossavi S","Freedman BI","Chen H","Murea M","Houston DK","Velazquez-Ramirez G","Bagwell B","Williams TK","Williamson JD","Robinson TW","Hurie JB","Geary RL","Rocco MV","Davis RP"],"additional_accession":[]},"is_claimable":false,"name":"A randomized pilot study to evaluate graft versus fistula vascular access strategy in older patients with advanced kidney disease: results of a feasibility study.","description":"Background
Although older adults encompass almost half of patients with advanced chronic kidney disease, it remains unclear which long-term hemodialysis vascular access type, arteriovenous fistula or arteriovenous graft, is optimal with respect to effectiveness and patient satisfaction. Clinical outcomes based on the initial AV access type have not been evaluated in randomized controlled trials. This pilot study tested the feasibility of randomizing older adults with advanced kidney disease to initial arteriovenous fistula versus graft vascular access surgery.Methods
Patients 65 years or older with pre-dialysis chronic kidney disease or incident end-stage kidney disease and no prior arteriovenous vascular access intervention were randomized in a 1:1 ratio to undergo surgica","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020","modification":"2025-04-26T22:52:55.075Z","creation":"2025-04-06T17:18:35.258Z"},"accession":"S-EPMC7298797","cross_references":{"pubmed":["32551134"],"doi":["10.1186/s40814-020-00619-9"]}}