biostudies-literatureUnknown40(8)Pittam B<h4>Objective</h4>To describe the prevalence of depression among patients with primary systemic vasculitides (PSV); compare prevalence according to vasculitis type and against controls; and examine the impact of depression on PSV outcomes.<h4>Methods</h4>We searched Medline, PubMed, Scopus and Web of Science using a predefined protocol in accordance with PRISMA guidelines. We included all studies that reported the prevalence or impact of depression in PSV. We also included polymyalgia rheumatica (PMR) given its association with giant cell arteritis (GCA). Meta-analyses of prevalence estimates were performed using random-effects models and reported as percentages (95% confidence interval).<h4>Results</h4>We reviewed a total of 15 studies that described the prevalence of depression, categoriRheumatology international1215-1221https://www.ebi.ac.uk/biostudies/studies/S-EPMC7316669biostudies-literatureThe prevalence and impact of depression in primary systemic vasculitis: a systematic review and meta-analysis.PMC7316669Gupta SZhao SSPittam BHughes DMAhmed AEfalseThe prevalence and impact of depression in primary systemic vasculitis: a systematic review and meta-analysis.<h4>Objective</h4>To describe the prevalence of depression among patients with primary systemic vasculitides (PSV); compare prevalence according to vasculitis type and against controls; and examine the impact of depression on PSV outcomes.<h4>Methods</h4>We searched Medline, PubMed, Scopus and Web of Science using a predefined protocol in accordance with PRISMA guidelines. We included all studies that reported the prevalence or impact of depression in PSV. We also included polymyalgia rheumatica (PMR) given its association with giant cell arteritis (GCA). Meta-analyses of prevalence estimates were performed using random-effects models and reported as percentages (95% confidence interval).<h4>Results</h4>We reviewed a total of 15 studies that described the prevalence of depression, categori2020-01-01T00:00:00Z2020 Aug2025-04-04T14:25:22.013Z2020-07-05T07:04:57ZS-EPMC73166693249488910.1007/s00296-020-04611-7