{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["19(7)"],"submitter":["Wu Y"],"funding":["Galderma"],"pubmed_abstract":["<h4>Background</h4>Patients are increasingly aware of the aesthetic appearance of aging hands.<h4>Aims</h4>To evaluate efficacy and safety of a hyaluronic acid gel for improving skin quality in aged skin of the dorsal hand.<h4>Methods</h4>This was a 15-month randomized, multi-center, evaluator-blinded, split-hand, no treatment-controlled study. Three treatments with hyaluronic acid gel were administered in the same hand in adult Chinese subjects with grade 2 or 3 (mild or moderate aging) on the Hand Grading Scale (HGS). The primary objective was to evaluate the difference at 3 months between treated and untreated hands, based on the blinded evaluator's HGS assessment. Secondary assessments included the Global Aesthetic Improvement Scale (GAIS), biophysical measurements (skin elasticity, sk"],"journal":["Journal of cosmetic dermatology"],"pagination":["1627-1635"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7318129"],"repository":["biostudies-literature"],"pubmed_title":["A randomized study showing improved skin quality and aesthetic appearance of dorsal hands after hyaluronic acid gel treatment in a Chinese population."],"pmcid":["PMC7318129"],"pubmed_authors":["Zhong S","Wang R","Tian Y","Wu W","Wu Y","Xu J"],"additional_accession":[]},"is_claimable":false,"name":"A randomized study showing improved skin quality and aesthetic appearance of dorsal hands after hyaluronic acid gel treatment in a Chinese population.","description":"<h4>Background</h4>Patients are increasingly aware of the aesthetic appearance of aging hands.<h4>Aims</h4>To evaluate efficacy and safety of a hyaluronic acid gel for improving skin quality in aged skin of the dorsal hand.<h4>Methods</h4>This was a 15-month randomized, multi-center, evaluator-blinded, split-hand, no treatment-controlled study. Three treatments with hyaluronic acid gel were administered in the same hand in adult Chinese subjects with grade 2 or 3 (mild or moderate aging) on the Hand Grading Scale (HGS). The primary objective was to evaluate the difference at 3 months between treated and untreated hands, based on the blinded evaluator's HGS assessment. Secondary assessments included the Global Aesthetic Improvement Scale (GAIS), biophysical measurements (skin elasticity, sk","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Jul","modification":"2025-06-01T02:42:58.976Z","creation":"2025-06-01T02:42:58.976Z"},"accession":"S-EPMC7318129","cross_references":{"pubmed":["31769596"],"doi":["10.1111/jocd.13221"]}}