{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Bumann EE"],"funding":["NIDCR NIH HHS","National Institute of Dental and Craniofacial Research"],"pagination":["125-128"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7328771"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["20 Suppl 1"],"pubmed_abstract":["Orthodontic tooth movement (OTM) relies on the orchestration of clinical and biologic events that include the application of clinical force followed by a cascade of cellular and molecular responses. Our understanding about OTM today has evolved from, and is largely based on historic studies. However, the advances in bone biology and clinical orthodontics today continue to pave the pathway towards an improved knowledge base, and state of the art therapeutics in OTM. Osteoblasts and osteoclasts have been the primary cells analyzed in OTM. However, the role of osteocytes, a cell previously thought to be static, should be considered in light of new findings in molecular biological research. Osteocytes are now known to be significant in controlling responses to mechanical forces and therefore m"],"journal":["Orthodontics & craniofacial research"],"pubmed_title":["A new cyte in orthodontics: Osteocytes in tooth movement."],"pmcid":["PMC7328771"],"funding_grant_id":["K08 DE021705"],"pubmed_authors":["Frazier-Bowers SA","Bumann EE"],"additional_accession":[]},"is_claimable":false,"name":"A new cyte in orthodontics: Osteocytes in tooth movement.","description":"Orthodontic tooth movement (OTM) relies on the orchestration of clinical and biologic events that include the application of clinical force followed by a cascade of cellular and molecular responses. Our understanding about OTM today has evolved from, and is largely based on historic studies. However, the advances in bone biology and clinical orthodontics today continue to pave the pathway towards an improved knowledge base, and state of the art therapeutics in OTM. Osteoblasts and osteoclasts have been the primary cells analyzed in OTM. However, the role of osteocytes, a cell previously thought to be static, should be considered in light of new findings in molecular biological research. Osteocytes are now known to be significant in controlling responses to mechanical forces and therefore m","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017 Jun","modification":"2025-05-18T12:52:00.509Z","creation":"2020-07-06T07:08:26Z"},"accession":"S-EPMC7328771","cross_references":{"pubmed":["28643925"],"doi":["10.1111/ocr.12176"]}}