biostudies-literatureUnknown12(5)Nam H<h4>Background</h4>The best ventilator mode for patients receiving non-invasive ventilation (NIV) has not been clarified. This study compared the effectiveness of two pressure-targeted modes, i.e., pressure support ventilation (PSV) and pressure-controlled ventilation (PCV), in patients receiving NIV.<h4>Methods</h4>This was a prospective multicentre observational study of NIV use for acute respiratory failure (ARF) in adult patients. We compared the two pressure-targeted modes in terms of NIV success and complication rates.<h4>Results</h4>Among 176 patients receiving NIV, 88 patients were included in the study (PCV mode, n=29; PSV mode, n=59). The study population had a median age of 73.0 years and median body mass index of 20.8 kg/m². The applied inspiratory positive airway prJournal of thoracic disease2553-2562https://www.ebi.ac.uk/biostudies/studies/S-EPMC7330335biostudies-literatureNon-invasive ventilation for acute respiratory failure: pressure support ventilation <i>vs.</i> pressure-controlled ventilation.PMC7330335Kim SWLee YSKang HKPark TSHa JHHwang JJLee KShin YMChang YPark SCho JHKorean NIV Study GroupNam HfalseNon-invasive ventilation for acute respiratory failure: pressure support ventilation <i>vs.</i> pressure-controlled ventilation.<h4>Background</h4>The best ventilator mode for patients receiving non-invasive ventilation (NIV) has not been clarified. This study compared the effectiveness of two pressure-targeted modes, i.e., pressure support ventilation (PSV) and pressure-controlled ventilation (PCV), in patients receiving NIV.<h4>Methods</h4>This was a prospective multicentre observational study of NIV use for acute respiratory failure (ARF) in adult patients. We compared the two pressure-targeted modes in terms of NIV success and complication rates.<h4>Results</h4>Among 176 patients receiving NIV, 88 patients were included in the study (PCV mode, n=29; PSV mode, n=59). The study population had a median age of 73.0 years and median body mass index of 20.8 kg/m². The applied inspiratory positive airway pr2020-01-01T00:00:00Z2020 May2025-04-22T02:05:09.407Z2025-04-05T20:14:49.011ZS-EPMC73303353264216310.21037/jtd.2020.03.27