{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12(5)"],"submitter":["Nappi F"],"pubmed_abstract":["The role of the aortic root is to convert the accumulated elastic energy during systole into kinetic flow energy during diastole, in order to improve blood distribution in the coronary tree. Therefore, the sinuses of Valsalva of the aortic root are not predisposed to accept any bulky material, especially in case of uncrushed solid calcific agglomerates. This concept underlines the differences between surgical aortic valve replacement, in which decalcification is a main part of the procedure, and transcatheter aortic valve replacement (TAVR). Cyclic changes in shape and size of the aortic root influence blood flow in the Valsalva sinuses. Recent papers have been investigating the dynamic changes of the aortic root and whether those differences might be correlated with clinical effects, and "],"journal":["Journal of thoracic disease"],"pagination":["2919-2925"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7330384"],"repository":["biostudies-literature"],"pubmed_title":["Are the dynamic changes of the aortic root determinant for thrombosis or leaflet degeneration after transcatheter aortic valve replacement?"],"pmcid":["PMC7330384"],"pubmed_authors":["Sing SSA","Nappi F","Timofeeva I","Chello M","Mihos C","Nenna A","Gentile F"],"additional_accession":[]},"is_claimable":false,"name":"Are the dynamic changes of the aortic root determinant for thrombosis or leaflet degeneration after transcatheter aortic valve replacement?","description":"The role of the aortic root is to convert the accumulated elastic energy during systole into kinetic flow energy during diastole, in order to improve blood distribution in the coronary tree. Therefore, the sinuses of Valsalva of the aortic root are not predisposed to accept any bulky material, especially in case of uncrushed solid calcific agglomerates. This concept underlines the differences between surgical aortic valve replacement, in which decalcification is a main part of the procedure, and transcatheter aortic valve replacement (TAVR). Cyclic changes in shape and size of the aortic root influence blood flow in the Valsalva sinuses. Recent papers have been investigating the dynamic changes of the aortic root and whether those differences might be correlated with clinical effects, and ","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 May","modification":"2025-04-22T02:05:24.303Z","creation":"2025-04-05T20:14:54.929Z"},"accession":"S-EPMC7330384","cross_references":{"pubmed":["32642204"],"doi":["10.21037/jtd.2020.02.01"]}}