{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Pikula J"],"funding":["Grantová Agentura České Republiky"],"pagination":["232"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7339577"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["16(1)"],"pubmed_abstract":["<h4>Background</h4>Emergence of both viral zoonoses from bats and diseases that threaten bat populations has highlighted the necessity for greater insights into the functioning of the bat immune system. Particularly when considering hibernating temperate bat species, it is important to understand the seasonal dynamics associated with immune response. Body temperature is one of the factors that modulates immune functions and defence mechanisms against pathogenic agents in vertebrates. To better understand innate immunity mediated by phagocytes in bats, we measured respiratory burst and haematology and blood chemistry parameters in heterothermic greater mouse-eared bats (Myotis myotis) and noctules (Nyctalus noctula) and homeothermic laboratory mice (Mus musculus).<h4>Results</h4>Bats displa"],"journal":["BMC veterinary research"],"pubmed_title":["Phagocyte activity reflects mammalian homeo- and hetero-thermic physiological states."],"pmcid":["PMC7339577"],"funding_grant_id":["17-20286S"],"pubmed_authors":["Nemcova M","Zajickova R","Piacek V","Pikula J","Bandouchova H","Kovacova V","Papezikova I","Zukal J","Heger T"],"additional_accession":[]},"is_claimable":false,"name":"Phagocyte activity reflects mammalian homeo- and hetero-thermic physiological states.","description":"<h4>Background</h4>Emergence of both viral zoonoses from bats and diseases that threaten bat populations has highlighted the necessity for greater insights into the functioning of the bat immune system. Particularly when considering hibernating temperate bat species, it is important to understand the seasonal dynamics associated with immune response. Body temperature is one of the factors that modulates immune functions and defence mechanisms against pathogenic agents in vertebrates. To better understand innate immunity mediated by phagocytes in bats, we measured respiratory burst and haematology and blood chemistry parameters in heterothermic greater mouse-eared bats (Myotis myotis) and noctules (Nyctalus noctula) and homeothermic laboratory mice (Mus musculus).<h4>Results</h4>Bats displa","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Jul","modification":"2026-07-15T23:35:11.732Z","creation":"2025-04-06T12:35:08.351Z"},"accession":"S-EPMC7339577","cross_references":{"pubmed":["32631329"],"doi":["10.1186/s12917-020-02450-z"]}}