{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["1(5)"],"submitter":["Schlottau K"],"pubmed_abstract":["<h4>Background</h4>In December, 2019, a novel zoonotic severe acute respiratory syndrome-related coronavirus emerged in China. The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) became pandemic within weeks and the number of human infections and severe cases is increasing. We aimed to investigate the susceptibilty of potential animal hosts and the risk of anthropozoonotic spill-over infections.<h4>Methods</h4>We intranasally inoculated nine fruit bats (<i>Rousettus aegyptiacus</i>), ferrets (<i>Mustela putorius</i>), pigs (<i>Sus scrofa domesticus</i>), and 17 chickens (<i>Gallus gallus domesticus</i>) with 10<sup>5</sup> TCID<sub>50</sub> of a SARS-CoV-2 isolate per animal. Direct contact animals (n=3) were included 24 h after inoculation to test viral transmission. An"],"journal":["The Lancet. Microbe"],"pagination":["e218-e225"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7340389"],"repository":["biostudies-literature"],"pubmed_title":["SARS-CoV-2 in fruit bats, ferrets, pigs, and chickens: an experimental transmission study."],"pmcid":["PMC7340389"],"pubmed_authors":["Sehl J","Schon J","Beer M","Grund C","Harder T","Balkema-Buschmann A","Breithaupt A","Hoffmann D","Rissmann M","Schlottau K","Wylezich C","Graaf A","Mettenleiter TC","Hoper D"],"additional_accession":[]},"is_claimable":false,"name":"SARS-CoV-2 in fruit bats, ferrets, pigs, and chickens: an experimental transmission study.","description":"<h4>Background</h4>In December, 2019, a novel zoonotic severe acute respiratory syndrome-related coronavirus emerged in China. The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) became pandemic within weeks and the number of human infections and severe cases is increasing. We aimed to investigate the susceptibilty of potential animal hosts and the risk of anthropozoonotic spill-over infections.<h4>Methods</h4>We intranasally inoculated nine fruit bats (<i>Rousettus aegyptiacus</i>), ferrets (<i>Mustela putorius</i>), pigs (<i>Sus scrofa domesticus</i>), and 17 chickens (<i>Gallus gallus domesticus</i>) with 10<sup>5</sup> TCID<sub>50</sub> of a SARS-CoV-2 isolate per animal. Direct contact animals (n=3) were included 24 h after inoculation to test viral transmission. An","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Sep","modification":"2026-04-12T19:36:40.718Z","creation":"2020-08-29T07:19:13Z"},"accession":"S-EPMC7340389","cross_references":{"pubmed":["32838346"],"doi":["10.1016/S2666-5247(20)30089-6"]}}