biostudies-literatureUnknown12(12)Bock JOCoronavirus disease 2019 (COVID-19), caused by an outbreak of the severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) in Wuhan, China, has led to an unprecedented health and economic crisis worldwide. To develop treatments that can stop or lessen the symptoms and severity of SARS-CoV-2 infection, it is critical to understand how the virus behaves inside human cells, and so far studies in this area remain scarce. A recent study investigated translatome and proteome host cell changes induced <i>in vitro</i> by SARS-CoV-2. Here, we use the publicly available proteomics data from this study to re-analyze the <i>in vitro</i> cellular consequences of SARS-CoV-2 infection by impact pathways analysis and network analysis. Notably, proteins linked to the inflammatory response, but also proAging11277-11286https://www.ebi.ac.uk/biostudies/studies/S-EPMC7343490biostudies-literatureRe-analysis of SARS-CoV-2-infected host cell proteomics time-course data by impact pathway analysis and network analysis: a potential link with inflammatory response.PMC7343490Ortea IBock JOfalseRe-analysis of SARS-CoV-2-infected host cell proteomics time-course data by impact pathway analysis and network analysis: a potential link with inflammatory response.Coronavirus disease 2019 (COVID-19), caused by an outbreak of the severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) in Wuhan, China, has led to an unprecedented health and economic crisis worldwide. To develop treatments that can stop or lessen the symptoms and severity of SARS-CoV-2 infection, it is critical to understand how the virus behaves inside human cells, and so far studies in this area remain scarce. A recent study investigated translatome and proteome host cell changes induced <i>in vitro</i> by SARS-CoV-2. Here, we use the publicly available proteomics data from this study to re-analyze the <i>in vitro</i> cellular consequences of SARS-CoV-2 infection by impact pathways analysis and network analysis. Notably, proteins linked to the inflammatory response, but also pro2020-01-01T00:00:00Z2020 Jun2025-04-22T19:30:45.706Z2020-10-01T07:04:57ZS-EPMC73434903257507610.18632/aging.103524