biostudies-literatureSchubert CDeutsche Forschungsgemeinschaft92https://www.ebi.ac.uk/biostudies/studies/S-EPMC7347580biostudies-literatureUnknown3Wrist-worn devices with heart rate monitoring have become increasingly popular. Although current guidelines advise to consider clinical symptoms and exercise tolerance during decision-making in heart disease, it remains unknown to which extent wearables can help to determine such functional capacity measures. In clinical settings, the 6-minute walk test has become a standardized diagnostic and prognostic marker. We aimed to explore, whether 6-minute walk distances can be predicted by wrist-worn devices in patients with different stages of mitral and aortic valve disease. A total of <i>n</i> = 107 sensor datasets with 1,019,748 min of recordings were analysed. Based on heart rate recordings and literature information, activity levels were determined and compared to results from a 6-minute wNPJ digital medicineWearable devices can predict the outcome of standardized 6-minute walk tests in heart disease.PMC7347580223533535Nordmeyer SArcher GHose RTonino PALFalk VRunte KBerger FKuehne THennemuth AKelm MSchubert CZelis JMTer Horst HfalseWearable devices can predict the outcome of standardized 6-minute walk tests in heart disease.Wrist-worn devices with heart rate monitoring have become increasingly popular. Although current guidelines advise to consider clinical symptoms and exercise tolerance during decision-making in heart disease, it remains unknown to which extent wearables can help to determine such functional capacity measures. In clinical settings, the 6-minute walk test has become a standardized diagnostic and prognostic marker. We aimed to explore, whether 6-minute walk distances can be predicted by wrist-worn devices in patients with different stages of mitral and aortic valve disease. A total of <i>n</i> = 107 sensor datasets with 1,019,748 min of recordings were analysed. Based on heart rate recordings and literature information, activity levels were determined and compared to results from a 6-minute w2020-01-01T00:00:00Z20202026-04-12T19:48:07.669Z2026-04-07T13:23:13.711ZS-EPMC73475803266597710.1038/s41746-020-0299-2