{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12(6)"],"submitter":["Borgonetti V"],"pubmed_abstract":["Mood disorders represent one of the most prevalent and costly psychiatric diseases worldwide. The current therapies are generally characterized by several well-known side effects which limit their prolonged use. The use of herbal medicine for the management of several psychiatric conditions is becoming more established, as it is considered a safer support to conventional pharmacotherapy. The aim of this study was to investigate the possible anxiolytic and antidepressant activity of a fixed combination of L-theanine, <i>Magnolia officinalis</i>, and <i>Melissa officinalis</i> (TMM) in an attempt to evaluate how the multiple modulations of different physiological systems may contribute to reducing mood disorders. TMM showed an anxiolytic-like and antidepressant-like activity in vivo, which w"],"journal":["Nutrients"],"pagination":["E1803"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7353338"],"repository":["biostudies-literature"],"pubmed_title":["Novel Therapeutic Approach for the Management of Mood Disorders: In Vivo and In Vitro Effect of a Combination of L-Theanine, <i>Melissa</i> <i>officinalis</i> L. and <i>Magnolia officinalis</i> Rehder & E.H. Wilson."],"pmcid":["PMC7353338"],"pubmed_authors":["Governa P","Biagi M","Galeotti N","Borgonetti V"],"additional_accession":[]},"is_claimable":false,"name":"Novel Therapeutic Approach for the Management of Mood Disorders: In Vivo and In Vitro Effect of a Combination of L-Theanine, <i>Melissa</i> <i>officinalis</i> L. and <i>Magnolia officinalis</i> Rehder & E.H. Wilson.","description":"Mood disorders represent one of the most prevalent and costly psychiatric diseases worldwide. The current therapies are generally characterized by several well-known side effects which limit their prolonged use. The use of herbal medicine for the management of several psychiatric conditions is becoming more established, as it is considered a safer support to conventional pharmacotherapy. The aim of this study was to investigate the possible anxiolytic and antidepressant activity of a fixed combination of L-theanine, <i>Magnolia officinalis</i>, and <i>Melissa officinalis</i> (TMM) in an attempt to evaluate how the multiple modulations of different physiological systems may contribute to reducing mood disorders. TMM showed an anxiolytic-like and antidepressant-like activity in vivo, which w","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Jun","modification":"2026-05-03T00:08:46.532Z","creation":"2020-11-22T12:30:37Z"},"accession":"S-EPMC7353338","cross_references":{"pubmed":["32560413"],"doi":["10.3390/nu12061803"]}}