{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Lee JY"],"funding":["Soonchunhyang University","National Research Foundation of Korea"],"pagination":["277"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7353728"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["20(1)"],"pubmed_abstract":["<h4>Background</h4>Dopamine transporter (DAT) imaging may enable clinicians to discriminate idiopathic normal pressure hydrocephalus (iNPH) from other parkinsonian disorders. However, a specific pattern of dopaminergic loss in DAT imaging of iNPH patients remains to be further elucidated.<h4>Methods</h4>In this preliminary study, 11 patients with iNPH in our hospital between March 2017 and February 2019 were finally enrolled. A diagnosis of iNPH was made according to the two established criteria. For visual analysis of DAT imaging, a striatum was divided into five domains. A semi-quantitative visual assessment was performed with a consensus between a nuclear medicine specialist and an experienced neurologist who were blinded to the clinical diagnosis.<h4>Results</h4>Striatal dopaminergic d"],"journal":["BMC neurology"],"pubmed_title":["Detailed visual assessment of striatal dopaminergic depletion in patients with idiopathic normal pressure hydrocephalus: unremarkable or not?"],"pmcid":["PMC7353728"],"funding_grant_id":["Not applicable","NRF-2018R1C1B5045312"],"pubmed_authors":["Ju H","Kwon KY","Park SB","Lee M","Lee JY","Im K"],"additional_accession":[]},"is_claimable":false,"name":"Detailed visual assessment of striatal dopaminergic depletion in patients with idiopathic normal pressure hydrocephalus: unremarkable or not?","description":"<h4>Background</h4>Dopamine transporter (DAT) imaging may enable clinicians to discriminate idiopathic normal pressure hydrocephalus (iNPH) from other parkinsonian disorders. However, a specific pattern of dopaminergic loss in DAT imaging of iNPH patients remains to be further elucidated.<h4>Methods</h4>In this preliminary study, 11 patients with iNPH in our hospital between March 2017 and February 2019 were finally enrolled. A diagnosis of iNPH was made according to the two established criteria. For visual analysis of DAT imaging, a striatum was divided into five domains. A semi-quantitative visual assessment was performed with a consensus between a nuclear medicine specialist and an experienced neurologist who were blinded to the clinical diagnosis.<h4>Results</h4>Striatal dopaminergic d","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Jul","modification":"2025-05-29T14:37:49.243Z","creation":"2024-10-19T04:22:10.374Z"},"accession":"S-EPMC7353728","cross_references":{"pubmed":["32652959"],"doi":["10.1186/s12883-020-01861-7"]}}