biostudies-literatureUnknown9(6)Mallamaci FSleep disordered breathing (SDB), as defined by the Apnea Hypopnea Index (AHI), is a highly prevalent disturbance in end stage kidney disease. SDB improves early on after renal transplantation but long-term changes in AHI in these patients have not been studied. We studied the long-term changes in AHI in a series of 221 renal transplant patients (mean age: 47 ± 12 years; 70% males) over a median follow up of 35 months. Data analysis was made by the generalized estimating equations method (GEE). On longitudinal observation, the median AHI rose from 1.8 (Interquartile range: 0.6-5.0) to 2.9 (IQR: 1.0-6.6) and to 3.6 (IQR: 1.7-10.4) at the second and third visit, respectively (p = 0.009 by the GEE model and the proportion of patients with moderate to severe SDB rose from 8% to 20%. LongitudinJournal of clinical medicineE1739https://www.ebi.ac.uk/biostudies/studies/S-EPMC7355565biostudies-literatureLong-Term Changes in Sleep Disordered Breathing in Renal Transplant Patients: Relevance of the BMI.PMC7355565Mallamaci FTripepi RMarino CVersace MCSanguedolce MCD'Arrigo GTripepi GPorto GZoccali CfalseLong-Term Changes in Sleep Disordered Breathing in Renal Transplant Patients: Relevance of the BMI.Sleep disordered breathing (SDB), as defined by the Apnea Hypopnea Index (AHI), is a highly prevalent disturbance in end stage kidney disease. SDB improves early on after renal transplantation but long-term changes in AHI in these patients have not been studied. We studied the long-term changes in AHI in a series of 221 renal transplant patients (mean age: 47 ± 12 years; 70% males) over a median follow up of 35 months. Data analysis was made by the generalized estimating equations method (GEE). On longitudinal observation, the median AHI rose from 1.8 (Interquartile range: 0.6-5.0) to 2.9 (IQR: 1.0-6.6) and to 3.6 (IQR: 1.7-10.4) at the second and third visit, respectively (p = 0.009 by the GEE model and the proportion of patients with moderate to severe SDB rose from 8% to 20%. Longitudin2020-01-01T00:00:00Z2020 Jun2025-04-19T18:01:46.108Z2025-04-19T18:01:46.108ZS-EPMC73555653251281610.3390/jcm9061739