{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["25(12)"],"submitter":["Diaconu D"],"pubmed_abstract":["Two new series of hybrid quinoline-sulfonamide complexes (M2+: Zn2+, Cu2+, Co2+ and Cd2+) derivatives (QSC) were designed, synthesized and tested for their antimicrobial activity. The synthesis is straightforward and efficient, involving two steps: acylation of aminoquinoline followed by complexation with metal acetate (Cu2+, Co2+ and Cd2+) or chloride (Zn2+). The synthesized QSC compounds were characterized by FTIR and NMR spectroscopy and by X-ray diffraction on single crystal. The QSC compounds were preliminary screened for their antibacterial and antifungal activity and the obtained results are very promising. In this respect, the hybrid N-(quinolin-8-yl)-4-chloro-benzenesulfonamide cadmium (II), considered as leading structure for further studies, has an excellent antibacterial activi"],"journal":["Molecules (Basel, Switzerland)"],"pagination":["E2946"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7356327"],"repository":["biostudies-literature"],"pubmed_title":["Hybrid Quinoline-Sulfonamide Complexes (M2+) Derivatives with Antimicrobial Activity."],"pmcid":["PMC7356327"],"pubmed_authors":["Antoci V","Mangalagiu V","Amariucai-Mantu D","Mangalagiu II","Diaconu D","Giuroiu CL"],"additional_accession":[]},"is_claimable":false,"name":"Hybrid Quinoline-Sulfonamide Complexes (M2+) Derivatives with Antimicrobial Activity.","description":"Two new series of hybrid quinoline-sulfonamide complexes (M2+: Zn2+, Cu2+, Co2+ and Cd2+) derivatives (QSC) were designed, synthesized and tested for their antimicrobial activity. The synthesis is straightforward and efficient, involving two steps: acylation of aminoquinoline followed by complexation with metal acetate (Cu2+, Co2+ and Cd2+) or chloride (Zn2+). The synthesized QSC compounds were characterized by FTIR and NMR spectroscopy and by X-ray diffraction on single crystal. The QSC compounds were preliminary screened for their antibacterial and antifungal activity and the obtained results are very promising. In this respect, the hybrid N-(quinolin-8-yl)-4-chloro-benzenesulfonamide cadmium (II), considered as leading structure for further studies, has an excellent antibacterial activi","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Jun","modification":"2025-04-27T02:50:13.478Z","creation":"2025-04-06T18:41:03.485Z"},"accession":"S-EPMC7356327","cross_references":{"pubmed":["32604828"],"doi":["10.3390/molecules25122946"]}}