{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10(1)"],"submitter":["Kim H"],"pubmed_abstract":["Aluminium hydroxide is a well-known adjuvant used in vaccines. Although it can enhance an adaptive immune response to a co-administered antigen, it causes adverse effects, including macrophagic myofasciitis (MMF), subcutaneous pseudolymphoma, and drug hypersensitivity. The object of this study is to demonstrate pediatric cases of aluminium hydroxide-induced diseases focusing on its rarity, under-recognition, and distinctive pathology. Seven child patients with biopsy-proven MMF were retrieved from the Seoul National University Hospital (SNUH) pathology archives from 2015 to 2019. The medical records and immunisation history were reviewed, and a full pathological muscle examination was carried out. The mean age was 1.7 years (8.9-40 months), who had records of vaccination against hepatitis "],"journal":["Scientific reports"],"pagination":["11834"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7366910"],"repository":["biostudies-literature"],"pubmed_title":["Macrophagic myofasciitis and subcutaneous pseudolymphoma caused by aluminium adjuvants."],"pmcid":["PMC7366910"],"pubmed_authors":["Park JW","Lim KY","Kim H","Park SH","Kang J"],"additional_accession":[]},"is_claimable":false,"name":"Macrophagic myofasciitis and subcutaneous pseudolymphoma caused by aluminium adjuvants.","description":"Aluminium hydroxide is a well-known adjuvant used in vaccines. Although it can enhance an adaptive immune response to a co-administered antigen, it causes adverse effects, including macrophagic myofasciitis (MMF), subcutaneous pseudolymphoma, and drug hypersensitivity. The object of this study is to demonstrate pediatric cases of aluminium hydroxide-induced diseases focusing on its rarity, under-recognition, and distinctive pathology. Seven child patients with biopsy-proven MMF were retrieved from the Seoul National University Hospital (SNUH) pathology archives from 2015 to 2019. The medical records and immunisation history were reviewed, and a full pathological muscle examination was carried out. The mean age was 1.7 years (8.9-40 months), who had records of vaccination against hepatitis ","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Jul","modification":"2025-04-29T10:49:37.297Z","creation":"2025-04-06T19:38:34.113Z"},"accession":"S-EPMC7366910","cross_references":{"pubmed":["32678281"],"doi":["10.1038/s41598-020-68849-8"]}}