{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["7(4)"],"submitter":["Gyoten T"],"pubmed_abstract":["Aims
The aim of this study was to compare the outcomes of surgical mitral valve repair or replacement (sMVR) and percutaneous edge-to-edge repair using MitraClip (pMVR) in patients with severe left ventricular dysfunction affected by functional mitral regurgitation (FMR).Methods and results
We retrospectively identified 132 patients with left ventricular ejection fraction (LVEF) ≦ 30% submitted to sMVR (n = 47) or pMVR (n = 85) for FMR at our centre from January 2013 to December 2017. To adjust for baseline imbalances, we used a propensity score matching by age, logistic EuroSCORE, and left ventricular end-systolic volume. After being matched, MitraClip therapy showed lower perioperative mortality and rate of complications yet increased residual mitral regurgitation (MR) gr"],"journal":["ESC heart failure"],"pagination":["1781-1790"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7373891"],"repository":["biostudies-literature"],"pubmed_title":["Outcome comparison of mitral valve surgery and MitraClip therapy in patients with severely reduced left ventricular dysfunction."],"pmcid":["PMC7373891"],"pubmed_authors":["Rochor K","Just S","Fritzsche D","Gyoten T","Herwig V","Schenk S","Harnath A","Messroghli D","Grimmig O"],"additional_accession":[]},"is_claimable":false,"name":"Outcome comparison of mitral valve surgery and MitraClip therapy in patients with severely reduced left ventricular dysfunction.","description":"Aims
The aim of this study was to compare the outcomes of surgical mitral valve repair or replacement (sMVR) and percutaneous edge-to-edge repair using MitraClip (pMVR) in patients with severe left ventricular dysfunction affected by functional mitral regurgitation (FMR).Methods and results
We retrospectively identified 132 patients with left ventricular ejection fraction (LVEF) ≦ 30% submitted to sMVR (n = 47) or pMVR (n = 85) for FMR at our centre from January 2013 to December 2017. To adjust for baseline imbalances, we used a propensity score matching by age, logistic EuroSCORE, and left ventricular end-systolic volume. After being matched, MitraClip therapy showed lower perioperative mortality and rate of complications yet increased residual mitral regurgitation (MR) gr","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Aug","modification":"2025-04-19T11:35:29.912Z","creation":"2025-04-19T11:35:29.912Z"},"accession":"S-EPMC7373891","cross_references":{"pubmed":["32445540"],"doi":["10.1002/ehf2.12741"]}}