biostudies-literatureLou YMNational Natural Science Foundation of Chinae001317https://www.ebi.ac.uk/biostudies/studies/S-EPMC7375424biostudies-literatureUnknown8(1)<h4>Introduction</h4>Brachial-ankle pulse wave velocity (ba-PWV), as a simple and easily measured marker of arterial stiffness, has not been prospectively explored for its role in type 2 diabetes mellitus (T2DM) risk among the general population. This study aimed to explore the association between baseline ba-PWV value and new-onset T2DM among Chinese adults.<h4>Research design and methods</h4>Using data from Xiaotangshan Hospital, we conducted a prospective cohort study among those who underwent annual or biennial health check-up examinations and who had their ba-PWV measured from 2009 to 2016. We explored the risk of new-onset T2DM across ba-PWV tertiles using Cox proportional-hazards regression analysis.<h4>Results</h4>Of 6122 adults (68.9% male; mean age: 51.0 (SD 13.0) years) without BMJ open diabetes research & careAssociation between brachial-ankle pulse wave velocity and risk of type 2 diabetes mellitus: results from a cohort study.PMC737542481602853Lou YMWang CYGao XPPing ZChen HELiao MQXu SZhao DMa JPZeng FFPeng XLWang LfalseAssociation between brachial-ankle pulse wave velocity and risk of type 2 diabetes mellitus: results from a cohort study.<h4>Introduction</h4>Brachial-ankle pulse wave velocity (ba-PWV), as a simple and easily measured marker of arterial stiffness, has not been prospectively explored for its role in type 2 diabetes mellitus (T2DM) risk among the general population. This study aimed to explore the association between baseline ba-PWV value and new-onset T2DM among Chinese adults.<h4>Research design and methods</h4>Using data from Xiaotangshan Hospital, we conducted a prospective cohort study among those who underwent annual or biennial health check-up examinations and who had their ba-PWV measured from 2009 to 2016. We explored the risk of new-onset T2DM across ba-PWV tertiles using Cox proportional-hazards regression analysis.<h4>Results</h4>Of 6122 adults (68.9% male; mean age: 51.0 (SD 13.0) years) without 2020-01-01T00:00:00Z2020 Jul2026-07-16T03:18:12.025Z2026-07-09T10:31:16.898ZS-EPMC73754243269911310.1136/bmjdrc-2020-001317