{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Kim SH"],"funding":["NIEHS NIH HHS","Korea Health Industry Development Institute"],"pagination":["e037780"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7375628"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["10(7)"],"pubmed_abstract":["<h4>Introduction</h4>Coronary CT angiography (CCTA) is widely used for non-invasive coronary artery evaluation, but it is limited in identifying the nature of functional characteristics that cause ischaemia. Recent computational fluid dynamic (CFD) techniques applied to CCTA images permit non-invasive computation of fractional flow reserve (FFR), a measure of lesion-specific ischaemia. However, this technology has limitations, such as long computational time and the need for expensive equipment, which hinder widespread use.<h4>Methods and analysis</h4>This study is a prospective, multicentre, comparative and confirmatory trial designed to evaluate the diagnostic performance of HeartMedi V.1.0, a novel CT-derived FFR measurement for the detection of haemodynamically significant coronary art"],"journal":["BMJ open"],"pubmed_title":["Validation of the diagnostic performance of 'HeartMedi V.1.0', a novel CT-derived fractional flow reserve measurement, for patients with coronary artery disease: a study protocol."],"pmcid":["PMC7375628"],"funding_grant_id":["27306C2006","HI17C2006"],"pubmed_authors":["Kang SH","Kwon KH","Youn TJ","Chung WY","Byun YS","Bae JW","Kim SH","Yoon CH","Doh JH","Park SD","Nam CW","Chae IH"],"additional_accession":[]},"is_claimable":false,"name":"Validation of the diagnostic performance of 'HeartMedi V.1.0', a novel CT-derived fractional flow reserve measurement, for patients with coronary artery disease: a study protocol.","description":"<h4>Introduction</h4>Coronary CT angiography (CCTA) is widely used for non-invasive coronary artery evaluation, but it is limited in identifying the nature of functional characteristics that cause ischaemia. Recent computational fluid dynamic (CFD) techniques applied to CCTA images permit non-invasive computation of fractional flow reserve (FFR), a measure of lesion-specific ischaemia. However, this technology has limitations, such as long computational time and the need for expensive equipment, which hinder widespread use.<h4>Methods and analysis</h4>This study is a prospective, multicentre, comparative and confirmatory trial designed to evaluate the diagnostic performance of HeartMedi V.1.0, a novel CT-derived FFR measurement for the detection of haemodynamically significant coronary art","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Jul","modification":"2026-06-03T03:26:30.277Z","creation":"2024-11-21T00:39:03.596Z"},"accession":"S-EPMC7375628","cross_references":{"pubmed":["32690748"],"doi":["10.1136/bmjopen-2020-037780"]}}