{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Carter ME"],"funding":["HHS | NIH | National Institute of General Medical Sciences","NCRR NIH HHS","USDA | National Institute of Food and Agriculture","NSF | BIO | Division of Integrative Organismal Systems","NIGMS NIH HHS"],"pagination":["17122-17129"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7382252"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["117(29)"],"pubmed_abstract":["Symbioses of bacteria with fungi have only recently been described and are poorly understood. In the symbiosis of <i>Mycetohabitans</i> (formerly <i>Burkholderia</i>) <i>rhizoxinica</i> with the fungus <i>Rhizopus microsporus</i>, bacterial type III (T3) secretion is known to be essential. Proteins resembling T3-secreted transcription activator-like (TAL) effectors of plant pathogenic bacteria are encoded in the three sequenced <i>Mycetohabitans</i> spp. genomes. TAL effectors nuclear-localize in plants, where they bind and activate genes important in disease. The Burkholderia TAL-like (Btl) proteins bind DNA but lack the N- and C-terminal regions, in which TAL effectors harbor their T3 and nuclear localization signals, and activation domain. We characterized a Btl protein, Btl19-13, and f"],"journal":["Proceedings of the National Academy of Sciences of the United States of America"],"pubmed_title":["A TAL effector-like protein of an endofungal bacterium increases the stress tolerance and alters the transcriptome of the host."],"pmcid":["PMC7382252"],"funding_grant_id":["S10 RR025502","IOS-1261004","R01GM098861","R01 GM098861","2018-67011-28015"],"pubmed_authors":["Sabol MR","Rinaldi FC","Pawlowska TE","Dubrow ZE","Bogdanove AJ","Carpenter SCD","Mondo SJ","Carter ME","Lastovetsky OA"],"additional_accession":[]},"is_claimable":false,"name":"A TAL effector-like protein of an endofungal bacterium increases the stress tolerance and alters the transcriptome of the host.","description":"Symbioses of bacteria with fungi have only recently been described and are poorly understood. In the symbiosis of <i>Mycetohabitans</i> (formerly <i>Burkholderia</i>) <i>rhizoxinica</i> with the fungus <i>Rhizopus microsporus</i>, bacterial type III (T3) secretion is known to be essential. Proteins resembling T3-secreted transcription activator-like (TAL) effectors of plant pathogenic bacteria are encoded in the three sequenced <i>Mycetohabitans</i> spp. genomes. TAL effectors nuclear-localize in plants, where they bind and activate genes important in disease. The Burkholderia TAL-like (Btl) proteins bind DNA but lack the N- and C-terminal regions, in which TAL effectors harbor their T3 and nuclear localization signals, and activation domain. We characterized a Btl protein, Btl19-13, and f","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Jul","modification":"2026-05-04T23:43:56.731Z","creation":"2020-11-07T10:08:21Z"},"accession":"S-EPMC7382252","cross_references":{"pubmed":["32632014"],"doi":["10.1073/pnas.2003857117"]}}