{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["58(8)"],"submitter":["Loeffelholz MJ"],"pubmed_abstract":["Nucleic acid amplification tests (NAATs) are the primary means of identifying acute infections caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Accurate and fast test results may permit more efficient use of protective and isolation resources and allow rapid therapeutic interventions. We evaluated the analytical and clinical performance characteristics of the Xpert Xpress SARS-CoV-2 (Xpert) test, a rapid, automated molecular test for SARS-CoV-2. Analytical sensitivity and specificity/interference were assessed with infectious SARS-CoV-2; other infectious coronavirus species, including SARS-CoV; and 85 nasopharyngeal swab specimens positive for other respiratory viruses, including endemic human coronaviruses (hCoVs). Clinical performance was assessed using 483 remnant"],"journal":["Journal of clinical microbiology"],"pagination":["e00926-20"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7383535"],"repository":["biostudies-literature"],"pubmed_title":["Multicenter Evaluation of the Cepheid Xpert Xpress SARS-CoV-2 Test."],"pmcid":["PMC7383535"],"pubmed_authors":["Rakeman JL","Kop J","Persing DH","Zhang N","Chakravorty S","Pawlotsky JM","Butler-Wu SM","Mostafa H","Singh S","Sin MLY","Fourati S","Banik S","Swaminathan S","Loeffelholz MJ","Banada PP","Carroll KC","McEwan A","Fowler RC","Pandey U","Kwiatkowski RW","Nguyen D","Nava A","Alland D","Perno CF","Davies E","Gaur R","Chu VC"],"additional_accession":[]},"is_claimable":false,"name":"Multicenter Evaluation of the Cepheid Xpert Xpress SARS-CoV-2 Test.","description":"Nucleic acid amplification tests (NAATs) are the primary means of identifying acute infections caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Accurate and fast test results may permit more efficient use of protective and isolation resources and allow rapid therapeutic interventions. We evaluated the analytical and clinical performance characteristics of the Xpert Xpress SARS-CoV-2 (Xpert) test, a rapid, automated molecular test for SARS-CoV-2. Analytical sensitivity and specificity/interference were assessed with infectious SARS-CoV-2; other infectious coronavirus species, including SARS-CoV; and 85 nasopharyngeal swab specimens positive for other respiratory viruses, including endemic human coronaviruses (hCoVs). Clinical performance was assessed using 483 remnant","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Jul","modification":"2025-04-04T07:40:35.316Z","creation":"2025-04-04T07:40:35.316Z"},"accession":"S-EPMC7383535","cross_references":{"pubmed":["32366669"],"doi":["10.1128/JCM.00926-20"]}}