biostudies-literatureGalstyan ADeutsche ForschungsgemeinschaftFundacja na rzecz Nauki PolskiejFonds der Chemischen IndustrieBasic Energy SciencesU.S. Department of Energy, Office of Science, Office of Basic Energy Sciences8262-8266https://www.ebi.ac.uk/biostudies/studies/S-EPMC7384002biostudies-literatureUnknown26(37)Free base, zinc and palladium π-extended porphyrins containing fused naphthalenediamide units were employed as photosensitizers in antimicrobial photodynamic therapy (aPDT). Their efficacy, assessed by photophysical and in vitro photobiological studies on Gram-positive bacteria, was found to depend on metal coordination, showing a dramatic enhancement of photosensitizing activity for the palladium complex.Chemistry (Weinheim an der Bergstrasse, Germany)π-Extended Donor-Acceptor Porphyrins and Metalloporphyrins for Antimicrobial Photodynamic Inactivation.PMC7384002661574TEAM POIR.04.04.00-00-5BF1/17-00GA 2362/2-1DE-FG02-99ER14999Stepien MZhylitskaya HGalstyan ADobrindt UMaurya YKWasielewski MRWu YLLis TBae YJfalseπ-Extended Donor-Acceptor Porphyrins and Metalloporphyrins for Antimicrobial Photodynamic Inactivation.Free base, zinc and palladium π-extended porphyrins containing fused naphthalenediamide units were employed as photosensitizers in antimicrobial photodynamic therapy (aPDT). Their efficacy, assessed by photophysical and in vitro photobiological studies on Gram-positive bacteria, was found to depend on metal coordination, showing a dramatic enhancement of photosensitizing activity for the palladium complex.2020-01-01T00:00:00Z2020 Jul2025-04-19T23:01:16.995Z2025-04-19T23:01:16.995ZS-EPMC73840023196814410.1002/chem.201905372