{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Harteveld AA"],"funding":["Stichting voor de Technische Wetenschappen","NICHD NIH HHS","Foundation for the National Institutes of Health","Wellcome Trust","Engineering and Physical Sciences Research Council"],"pagination":["1828-1843"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7384055"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["84(4)"],"pubmed_abstract":["<h4>Purpose</h4>Placental function is key for successful human pregnancies. Perfusion may be a sensitive marker for the in vivo assessment of placental function. Arterial spin labeling (ASL) MRI enables noninvasive measurement of tissue perfusion and it was recently suggested that ASL with velocity-selective (VS) labeling could be advantageous in the placenta. We systematically evaluated essential VS-ASL sequence parameters to determine optimal settings for efficient placental perfusion measurements.<h4>Methods</h4>Eleven pregnant women were scanned at 3T using VS-ASL with 2D multislice echo planar imaging (EPI)-readout. One reference VS-ASL scan was acquired in all subjects; within subgroups the following parameters were systematically varied: cutoff velocity, velocity encoding direction,"],"journal":["Magnetic resonance in medicine"],"pubmed_title":["Systematic evaluation of velocity-selective arterial spin labeling settings for placental perfusion measurement."],"pmcid":["PMC7384055"],"funding_grant_id":["Human Placenta Project, 1U01HD087202‐01","201374/Z/16/Z","U01 HD087202","N018702 and M020533","14951","Sir Henry Wellcome Fellowship, 201374/Z/16/Z","WT 203148/Z/16/Z"],"pubmed_authors":["Rutherford M","van Osch MJP","Hutter J","Franklin SL","Hajnal JV","Jackson LH","Harteveld AA","De Vita E","Bos C"],"additional_accession":[]},"is_claimable":false,"name":"Systematic evaluation of velocity-selective arterial spin labeling settings for placental perfusion measurement.","description":"<h4>Purpose</h4>Placental function is key for successful human pregnancies. Perfusion may be a sensitive marker for the in vivo assessment of placental function. Arterial spin labeling (ASL) MRI enables noninvasive measurement of tissue perfusion and it was recently suggested that ASL with velocity-selective (VS) labeling could be advantageous in the placenta. We systematically evaluated essential VS-ASL sequence parameters to determine optimal settings for efficient placental perfusion measurements.<h4>Methods</h4>Eleven pregnant women were scanned at 3T using VS-ASL with 2D multislice echo planar imaging (EPI)-readout. One reference VS-ASL scan was acquired in all subjects; within subgroups the following parameters were systematically varied: cutoff velocity, velocity encoding direction,","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Oct","modification":"2025-04-19T23:01:57.758Z","creation":"2025-04-19T23:01:57.758Z"},"accession":"S-EPMC7384055","cross_references":{"pubmed":["32141655"],"doi":["10.1002/mrm.28240"]}}