{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["144(6)"],"submitter":["Malmgren L"],"pubmed_abstract":["<h4>Background/aims</h4>Prospective data on age-related changes in kidney function are required, especially since the current Kidney Disease Improving Global Outcomes (KDIGO) definition has been suggested to classify a large number of elderly people with CKD.<h4>Objective</h4>This study, a complement to our previous Cr-based study in the same cohort, is aimed at evaluating cystatin C (cysC)-based changes in kidney function during aging in older women and analyzing the association between CKD and mortality through 10 years of follow-up.<h4>Methods</h4>cysC was available in 981 women from the Osteoporosis Prospective Risk Assessment (OPRA) cohort, all aged 75 years on entry. Reinvestigations were made after 5 (n = 685) and 10 years (n = 365). Kidney function was estimated (estimated glomerul"],"journal":["Nephron"],"pagination":["290-298"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7384338"],"repository":["biostudies-literature"],"pubmed_title":["Longitudinal Changes in Kidney Function Estimated from Cystatin C and Its Association with Mortality in Elderly Women."],"pmcid":["PMC7384338"],"pubmed_authors":["Malmgren L","McGuigan FE","Christensson A","Akesson KE"],"additional_accession":[]},"is_claimable":false,"name":"Longitudinal Changes in Kidney Function Estimated from Cystatin C and Its Association with Mortality in Elderly Women.","description":"<h4>Background/aims</h4>Prospective data on age-related changes in kidney function are required, especially since the current Kidney Disease Improving Global Outcomes (KDIGO) definition has been suggested to classify a large number of elderly people with CKD.<h4>Objective</h4>This study, a complement to our previous Cr-based study in the same cohort, is aimed at evaluating cystatin C (cysC)-based changes in kidney function during aging in older women and analyzing the association between CKD and mortality through 10 years of follow-up.<h4>Methods</h4>cysC was available in 981 women from the Osteoporosis Prospective Risk Assessment (OPRA) cohort, all aged 75 years on entry. Reinvestigations were made after 5 (n = 685) and 10 years (n = 365). Kidney function was estimated (estimated glomerul","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020","modification":"2025-04-19T23:04:48.648Z","creation":"2025-04-19T23:04:48.648Z"},"accession":"S-EPMC7384338","cross_references":{"pubmed":["32392561"],"doi":["10.1159/000507256"]}}