{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Sato Y"],"funding":["Ministry of Health, Labour and Welfare","Japan Agency for Medical Research and Development"],"pagination":["e0236602"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7384644"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15(7)"],"pubmed_abstract":["A significant relationship exists between elevated uric acid concentration and both prevalent and incident hypertension; however, data regarding the influence of higher uric acid concentration at baseline on blood pressure control by antihypertensive drugs is scarce. Thus, a prospective cohort study was performed. The study outcome was the non-attainment of optimal blood pressure (NOBP). NOBP level was defined according to the Japanese hypertension guideline. This study enrolled a Japanese community-based cohort (N = 8,664; age 65.5 ± 6.4 years; women, 55.0%) who were not using antihypertensive drugs on the first visit for a health check-up program but started using antihypertensive drug(s) on the next-year visit. The participants were classified into quartiles based basic uric acid concen"],"journal":["PloS one"],"pubmed_title":["Higher baseline uric acid concentration is associated with non-attainment of optimal blood pressure."],"pmcid":["PMC7384644"],"funding_grant_id":["JP17ek0310005, JP18ek0310010, JP19ek0310010 and JP18lk1010033","H20-Junkankitou (Seishu)・Ippan-008 and H24-Nanchitou (Jin)・Ippan-006"],"pubmed_authors":["Kasahara M","Iseki K","Asahi K","Watanabe T","Fujimoto S","Konta T","Tsuruya K","Sato Y","Yamagata K","Shibagaki Y","Moriyama T","Kondo M","Narita I"],"additional_accession":[]},"is_claimable":false,"name":"Higher baseline uric acid concentration is associated with non-attainment of optimal blood pressure.","description":"A significant relationship exists between elevated uric acid concentration and both prevalent and incident hypertension; however, data regarding the influence of higher uric acid concentration at baseline on blood pressure control by antihypertensive drugs is scarce. Thus, a prospective cohort study was performed. The study outcome was the non-attainment of optimal blood pressure (NOBP). NOBP level was defined according to the Japanese hypertension guideline. This study enrolled a Japanese community-based cohort (N = 8,664; age 65.5 ± 6.4 years; women, 55.0%) who were not using antihypertensive drugs on the first visit for a health check-up program but started using antihypertensive drug(s) on the next-year visit. The participants were classified into quartiles based basic uric acid concen","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020","modification":"2025-04-21T17:58:00.932Z","creation":"2025-04-05T17:03:23.926Z"},"accession":"S-EPMC7384644","cross_references":{"pubmed":["32716977"],"doi":["10.1371/journal.pone.0236602"]}}