biostudies-literature00460Ashikbayeva ZNanoSlimSMARTERFDA HHSNice-DREAMEPICGuideLASEROPTIMAL@POLIMI12593https://www.ebi.ac.uk/biostudies/studies/S-EPMC7387462biostudies-literatureUnknown10(1)The high demand in effective and minimally invasive cancer treatments, namely thermal ablation, leads to the demand for real-time multi-dimensional thermometry to evaluate the treatment effectiveness, which can be also assisted by the use of nanoparticles. We report the results of 20-nm gold and magnetic iron oxide nanoparticles-assisted laser ablation on a porcine liver phantom. The experimental set-up consisting of high-scattering nanoparticle-doped fibers was operated by means of a scattering-level multiplexing arrangement and interrogated via optical backscattered reflectometry, together with a solid-state laser diode operating at 980 nm. The multiplexed 2-dimensional fiber arrangement based on nanoparticle-doped fibers allowed an accurate superficial thermal map detected in real-time.Scientific reportsDistributed 2D temperature sensing during nanoparticles assisted laser ablation by means of high-scattering fiber sensors.PMC7387462240919FD3908ANR-17-CE08-0002091019CRP2117R01 FD003908Rif. 2017-2075ANR-14-CE07-0016-03Jelbuldina MInglezakis VJBlanc WBeisenova ASaccomandi PMolardi CIssatayeva AAitkulov AAshikbayeva ZTosi D46falseDistributed 2D temperature sensing during nanoparticles assisted laser ablation by means of high-scattering fiber sensors.The high demand in effective and minimally invasive cancer treatments, namely thermal ablation, leads to the demand for real-time multi-dimensional thermometry to evaluate the treatment effectiveness, which can be also assisted by the use of nanoparticles. We report the results of 20-nm gold and magnetic iron oxide nanoparticles-assisted laser ablation on a porcine liver phantom. The experimental set-up consisting of high-scattering nanoparticle-doped fibers was operated by means of a scattering-level multiplexing arrangement and interrogated via optical backscattered reflectometry, together with a solid-state laser diode operating at 980 nm. The multiplexed 2-dimensional fiber arrangement based on nanoparticle-doped fibers allowed an accurate superficial thermal map detected in real-time.2020-01-01T00:00:00Z2020 Jul2024-10-17T15:35:40.998Z2020-10-02T07:25:54ZS-EPMC73874623272405310.1038/s41598-020-69384-2