biostudies-literatureChen XDiscipline Promotion Project of Xijing Hospitalthe National Natural Science Foundation of China195https://www.ebi.ac.uk/biostudies/studies/S-EPMC7388495biostudies-literatureUnknown15(1)<h4>Background</h4>Hyperbilirubinemia is one of the common complications after cardiac surgery and is associated with increased mortality. However, to the best of our knowledge, the reports on clinical significance of postoperative severe hyperbilirubinemia in Stanford type A aortic dissection (AAD) patients were limited.<h4>Methods</h4>Patients who underwent surgical treatment for AAD in our center between January 2015 and December 2018 were retrospectively screened. In-hospital mortality, long-term mortality, acute kidney injury (AKI), and the requirement of continuous renal replacement therapy (CRRT) were assessed as endpoints. Univariate and multivariate regression models were employed to identify the risk factors of these endpoints.<h4>Results</h4>After screening, 271 patients were inJournal of cardiothoracic surgeryCharacteristics and outcomes of Stanford type A aortic dissection patients with severe post-operation hyperbilirubinemia: a retrospective cohort study.PMC7388495XJZT18ML1681700584Zhang WLi YZhao LSun SBai MChen XMa FYu YfalseCharacteristics and outcomes of Stanford type A aortic dissection patients with severe post-operation hyperbilirubinemia: a retrospective cohort study.<h4>Background</h4>Hyperbilirubinemia is one of the common complications after cardiac surgery and is associated with increased mortality. However, to the best of our knowledge, the reports on clinical significance of postoperative severe hyperbilirubinemia in Stanford type A aortic dissection (AAD) patients were limited.<h4>Methods</h4>Patients who underwent surgical treatment for AAD in our center between January 2015 and December 2018 were retrospectively screened. In-hospital mortality, long-term mortality, acute kidney injury (AKI), and the requirement of continuous renal replacement therapy (CRRT) were assessed as endpoints. Univariate and multivariate regression models were employed to identify the risk factors of these endpoints.<h4>Results</h4>After screening, 271 patients were in2020-01-01T00:00:00Z2020 Jul2025-04-05T15:20:56.039Z2020-11-19T08:19:33ZS-EPMC73884953272339010.1186/s13019-020-01243-7