{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["15(7)"],"submitter":["Frazao DR"],"pubmed_abstract":["<h4>Background</h4>Periodontitis is a multifactorial inflammatory disease of tooth supporting tissues caused by oral biofilms, influenced by environmental and genetic factors, among others. Ethanol consumption has been considered a factor that enhances alveolar bone loss, especially in high doses. The present study aims to investigate the changes promoted by ethanol binge drinking per se or associated with ligature-induced periodontal breakdown on alveolar bone loss.<h4>Materials and methods</h4>Thirty-two Wistar rats were randomly allocated into four groups: control (C), ethanol (3g/kg/day; 3 days On-4 days Off protocol by gavage for 28 days, EtOH), experimental periodontitis (EP) and experimental periodontitis plus ethanol administration (EP+EtOH). On day 14th, periodontitis was induced "],"journal":["PloS one"],"pagination":["e0236161"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7392256"],"repository":["biostudies-literature"],"pubmed_title":["Ethanol binge drinking exposure affects alveolar bone quality and aggravates bone loss in experimentally-induced periodontitis."],"pmcid":["PMC7392256"],"pubmed_authors":["Monteiro D","Martins MD","Collares FM","Maia CDSF","Rosing CK","Frazao DR","Ferreira RO","Lima RR","Chemelo VDS","Balbinot GS","Bittencourt LO"],"additional_accession":[]},"is_claimable":false,"name":"Ethanol binge drinking exposure affects alveolar bone quality and aggravates bone loss in experimentally-induced periodontitis.","description":"<h4>Background</h4>Periodontitis is a multifactorial inflammatory disease of tooth supporting tissues caused by oral biofilms, influenced by environmental and genetic factors, among others. Ethanol consumption has been considered a factor that enhances alveolar bone loss, especially in high doses. The present study aims to investigate the changes promoted by ethanol binge drinking per se or associated with ligature-induced periodontal breakdown on alveolar bone loss.<h4>Materials and methods</h4>Thirty-two Wistar rats were randomly allocated into four groups: control (C), ethanol (3g/kg/day; 3 days On-4 days Off protocol by gavage for 28 days, EtOH), experimental periodontitis (EP) and experimental periodontitis plus ethanol administration (EP+EtOH). On day 14th, periodontitis was induced ","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020","modification":"2025-04-25T18:34:22.871Z","creation":"2025-04-06T07:37:49.497Z"},"accession":"S-EPMC7392256","cross_references":{"pubmed":["32730269"],"doi":["10.1371/journal.pone.0236161"]}}