biostudies-literatureRajamaki MLCancer Foundation Finland sr355https://www.ebi.ac.uk/biostudies/studies/S-EPMC7392702biostudies-literatureUnknown20(1)<h4>Background</h4>Infection of plants by viruses interferes with expression and subcellular localization of plant proteins. Potyviruses comprise the largest and most economically damaging group of plant-infecting RNA viruses. In virus-infected cells, at least two potyviral proteins localize to nucleus but reasons remain partly unknown.<h4>Results</h4>In this study, we examined changes in the nuclear proteome of leaf cells from a diploid potato line (Solanum tuberosum L.) after infection with potato virus A (PVA; genus Potyvirus; Potyviridae) and compared the data with that acquired for healthy leaves. Gel-free liquid chromatography-coupled to tandem mass spectrometry was used to identify 807 nuclear proteins in the potato line v2-108; of these proteins, 370 were detected in at least two sBMC plant biologyNuclear proteome of virus-infected and healthy potato leaves.PMC7392702190160Varjosalo MValkonen JPTSikorskaite-Gudziuniene SRajamaki MLSarmah NfalseNuclear proteome of virus-infected and healthy potato leaves.<h4>Background</h4>Infection of plants by viruses interferes with expression and subcellular localization of plant proteins. Potyviruses comprise the largest and most economically damaging group of plant-infecting RNA viruses. In virus-infected cells, at least two potyviral proteins localize to nucleus but reasons remain partly unknown.<h4>Results</h4>In this study, we examined changes in the nuclear proteome of leaf cells from a diploid potato line (Solanum tuberosum L.) after infection with potato virus A (PVA; genus Potyvirus; Potyviridae) and compared the data with that acquired for healthy leaves. Gel-free liquid chromatography-coupled to tandem mass spectrometry was used to identify 807 nuclear proteins in the potato line v2-108; of these proteins, 370 were detected in at least two s2020-01-01T00:00:00Z2020 Jul2025-04-04T22:32:09.226Z2020-10-04T07:16:53ZS-EPMC73927023272736110.1186/s12870-020-02561-7