{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Pikun NV"],"funding":["State Education Development Agency Republic of Latvia"],"pagination":["E3143"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7397266"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["25(14)"],"pubmed_abstract":["New fluorinated 3,6-dihydropyridines were obtained by the electrophilic fluorination of 1,2-dihydropyridines with Selectfluor®. These 3-fluoro-3,6-dihydropyridines were easily converted to corresponding pyridines by the elimination of hydrogen fluoride under mild conditions. A new approach to the synthesis of methyl 2-(fluoromethyl)-5-nitro-6-arylnicotinates by the fluorination of 3-fluoro-2-methyl-5-nitro-3,6-dihydropyridines or 1,2-dihydropyridines with Selectfluor® has been developed."],"journal":["Molecules (Basel, Switzerland)"],"pubmed_title":["Synthesis of Fluorinated 3,6-Dihydropyridines and 2-(Fluoromethyl)pyridines by Electrophilic Fluorination of 1,2-Dihydropyridines with Selectfluor®."],"pmcid":["PMC7397266"],"funding_grant_id":["PostDoc project Nr.1.1.1.2/VIAA/2/18/373"],"pubmed_authors":["Vigante B","Petrova M","Sobolev A","Pajuste K","Pikun NV","Plotniece A","Shermolovich YG","Muhamadejev R","Rucins M"],"additional_accession":[]},"is_claimable":false,"name":"Synthesis of Fluorinated 3,6-Dihydropyridines and 2-(Fluoromethyl)pyridines by Electrophilic Fluorination of 1,2-Dihydropyridines with Selectfluor®.","description":"New fluorinated 3,6-dihydropyridines were obtained by the electrophilic fluorination of 1,2-dihydropyridines with Selectfluor®. These 3-fluoro-3,6-dihydropyridines were easily converted to corresponding pyridines by the elimination of hydrogen fluoride under mild conditions. A new approach to the synthesis of methyl 2-(fluoromethyl)-5-nitro-6-arylnicotinates by the fluorination of 3-fluoro-2-methyl-5-nitro-3,6-dihydropyridines or 1,2-dihydropyridines with Selectfluor® has been developed.","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Jul","modification":"2025-04-04T08:20:06.709Z","creation":"2025-04-04T08:20:06.709Z"},"accession":"S-EPMC7397266","cross_references":{"pubmed":["32660085"],"doi":["10.3390/molecules25143143"]}}