biostudies-literatureLittle MMedical Research CouncilNational Institute for Health Research (NIHR)e034950https://www.ebi.ac.uk/biostudies/studies/S-EPMC7412604biostudies-literatureUnknown10(8)<h4>Objectives</h4>This systematic review aims to assess the quality of literature supporting surgical interventions for paediatric extravasation injury and to determine whether there is sufficient evidence to support invasive techniques in children.<h4>Methods</h4>We performed a systematic review by searching Ovid MEDLINE and EMBASE as well as AMED, CINAHL, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews and clinicaltrials.gov from inception to February 2019. Studies other than case reports were eligible for inclusion if the population was younger than 18 years old, if there was a surgical intervention aimed at treating extravasation injury and if they reported on outcomes. Study quality was graded according to the National Institutes of Health studBMJ openSurgical intervention for paediatric infusion-related extravasation injury: a systematic review.PMC7412604MR/N008405/1ACF-2017-13-009Jain AGardiner MGale CDupre SLittle MWormald JCRfalseSurgical intervention for paediatric infusion-related extravasation injury: a systematic review.<h4>Objectives</h4>This systematic review aims to assess the quality of literature supporting surgical interventions for paediatric extravasation injury and to determine whether there is sufficient evidence to support invasive techniques in children.<h4>Methods</h4>We performed a systematic review by searching Ovid MEDLINE and EMBASE as well as AMED, CINAHL, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews and clinicaltrials.gov from inception to February 2019. Studies other than case reports were eligible for inclusion if the population was younger than 18 years old, if there was a surgical intervention aimed at treating extravasation injury and if they reported on outcomes. Study quality was graded according to the National Institutes of Health stud2020-01-01T00:00:00Z2020 Aug2025-04-05T15:59:23.208Z2025-02-19T00:59:17.878ZS-EPMC74126043276408310.1136/bmjopen-2019-034950