{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Cao Y"],"funding":["Xi’an Science and Technology program under Grant","Natural Science Basic Research Plan in Shaanxi Province of China","Xi’an Science and Technology program","Fundamental Research Funds for the Central Universities under Grant","Xi'an Science and Technology program under Grant","Natural Science Foundation of Sichuan Province","Xi'an Science and Technology program"],"pagination":["215"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7425010"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["20(1)"],"pubmed_abstract":["<h4>Background</h4>Tumor necrosis factor-α (TNF-α) has been reported to play a part in the development of obstructive sleep apnea (OSA) and its complications. However, the relationship between TNF-α and OSA still remains inconclusive. We aimed to systematically review and synthesize studies published to date on association between the two in adults.<h4>Methods</h4>We searched for English-language articles containing original human data from case-control study studies in adults≥18 years of age. The selection criteria were set according to the PICOS framework. Articles were independently reviewed by three investigators. Data regarding demographics, clinical characteristics, and TNF-α levels were obtained. A random-effects model was applied to evaluate the overall effect sizes by calculating "],"journal":["BMC pulmonary medicine"],"pubmed_title":["Association between tumor necrosis factor alpha and obstructive sleep apnea in adults: a meta-analysis update."],"pmcid":["PMC7425010"],"funding_grant_id":["J20170219II","Program No.2020JQ-543; 2020JQ-927","SF1510(4)","2019YJ0067","xzy012019129"],"pubmed_authors":["Ning P","Cao Y","Wu S","Li Q","Zhang L","Quan J","Song Y"],"additional_accession":[]},"is_claimable":false,"name":"Association between tumor necrosis factor alpha and obstructive sleep apnea in adults: a meta-analysis update.","description":"<h4>Background</h4>Tumor necrosis factor-α (TNF-α) has been reported to play a part in the development of obstructive sleep apnea (OSA) and its complications. However, the relationship between TNF-α and OSA still remains inconclusive. We aimed to systematically review and synthesize studies published to date on association between the two in adults.<h4>Methods</h4>We searched for English-language articles containing original human data from case-control study studies in adults≥18 years of age. The selection criteria were set according to the PICOS framework. Articles were independently reviewed by three investigators. Data regarding demographics, clinical characteristics, and TNF-α levels were obtained. A random-effects model was applied to evaluate the overall effect sizes by calculating ","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Aug","modification":"2025-04-19T00:41:19.899Z","creation":"2025-04-07T11:41:02.646Z"},"accession":"S-EPMC7425010","cross_references":{"pubmed":["32787816"],"doi":["10.1186/s12890-020-01253-0"]}}