biostudies-literatureChan PSNHLBI NIH HHSe014837https://www.ebi.ac.uk/biostudies/studies/S-EPMC7428602biostudies-literatureUnknown9(7)Background Sustained return of spontaneous circulation (ROSC) is the most proximal and direct assessment of acute resuscitation quality in hospitals. However, validated tools to benchmark hospital rates for ROSC after in-hospital cardiac arrest currently do not exist. Methods and Results Within the national Get With The Guidelines-Resuscitation registry, we identified 83 206 patients admitted from 335 hospitals from 2014 to 2017 with in-hospital cardiac arrest. Using hierarchical logistic regression, we derived and validated a model for ROSC, defined as spontaneous and sustained ROSC for ≥20 consecutive minutes, from 24 pre-arrest variables and calculated rates of risk-standardized ROSC for in-hospital cardiac arrest for each hospital. Overall, rates of ROSC were 72.0% and 72.7% for the deJournal of the American Heart AssociationRisk-Standardizing Rates of Return of Spontaneous Circulation for In-Hospital Cardiac Arrest to Facilitate Hospital Comparisons.PMC7428602R01 HL123980Chan PSTang YAmerican Heart Association's Get With the Guidelines®‐Resuscitation InvestigatorsfalseRisk-Standardizing Rates of Return of Spontaneous Circulation for In-Hospital Cardiac Arrest to Facilitate Hospital Comparisons.Background Sustained return of spontaneous circulation (ROSC) is the most proximal and direct assessment of acute resuscitation quality in hospitals. However, validated tools to benchmark hospital rates for ROSC after in-hospital cardiac arrest currently do not exist. Methods and Results Within the national Get With The Guidelines-Resuscitation registry, we identified 83 206 patients admitted from 335 hospitals from 2014 to 2017 with in-hospital cardiac arrest. Using hierarchical logistic regression, we derived and validated a model for ROSC, defined as spontaneous and sustained ROSC for ≥20 consecutive minutes, from 24 pre-arrest variables and calculated rates of risk-standardized ROSC for in-hospital cardiac arrest for each hospital. Overall, rates of ROSC were 72.0% and 72.7% for the de2020-01-01T00:00:00Z2020 Apr2025-04-18T14:55:00.72Z2025-04-07T01:18:22.489ZS-EPMC74286023220071610.1161/JAHA.119.014837