{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Plow M"],"funding":["Patient-Centered Outcomes Research Institute"],"pagination":["e035470"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7430436"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["10(8)"],"pubmed_abstract":["<h4>Introduction</h4>Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system. It is considered a major cause of non-traumatic disability in young adults. One of the most common and disabling symptoms of MS is fatigue. MS fatigue can impact all aspects of quality of life, including physical, mental and social function. Fortunately, fatigue self-management interventions, such as '<i>Managing Fatigue: A 6 week energy conservation course'</i>, can decrease the impact of fatigue and improve health-related quality of life. The purpose of this study is to compare three modes of delivering the <i>Managing Fatigue</i> intervention-two remote delivery formats (teleconference and internet) and one in-person format-on perceptions of fatigue and its impact on physical, menta"],"journal":["BMJ open"],"pubmed_title":["REFRESH protocol: a non-inferiority randomised clinical trial comparing internet and teleconference to in-person 'Managing Fatigue' interventions on the impact of fatigue among persons with multiple sclerosis."],"pmcid":["PMC7430436"],"funding_grant_id":["MS-1610-37015"],"pubmed_authors":["Sattar A","Mathiowetz VG","Ghahari S","Packer T","Plow M","Bethoux F","Finlayson M","Preissner K"],"additional_accession":[]},"is_claimable":false,"name":"REFRESH protocol: a non-inferiority randomised clinical trial comparing internet and teleconference to in-person 'Managing Fatigue' interventions on the impact of fatigue among persons with multiple sclerosis.","description":"<h4>Introduction</h4>Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system. It is considered a major cause of non-traumatic disability in young adults. One of the most common and disabling symptoms of MS is fatigue. MS fatigue can impact all aspects of quality of life, including physical, mental and social function. Fortunately, fatigue self-management interventions, such as '<i>Managing Fatigue: A 6 week energy conservation course'</i>, can decrease the impact of fatigue and improve health-related quality of life. The purpose of this study is to compare three modes of delivering the <i>Managing Fatigue</i> intervention-two remote delivery formats (teleconference and internet) and one in-person format-on perceptions of fatigue and its impact on physical, menta","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Aug","modification":"2026-05-09T03:38:31.036Z","creation":"2020-08-29T07:24:03Z"},"accession":"S-EPMC7430436","cross_references":{"pubmed":["32801193"],"doi":["10.1136/bmjopen-2019-035470"]}}