{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9(4)"],"submitter":["Rades D"],"pubmed_abstract":["<h4>Background</h4>Prognostic tools estimating survival of elderly patients with cerebral metastases from small-cell lung cancer (SCLC) improve treatment personalization. A specific tool for these patients was developed and compared to existing instruments.<h4>Methods</h4>One-hundred-and-forty elderly patients (≥65 years) receiving whole-brain irradiation (WBI) for cerebral metastases from SCLC were retrospectively evaluated. WBI-program, age, gender, Karnofsky performance score, number of cerebral lesions, extracerebral metastases, and interval between SCLC-diagnosis and WBI were investigated. Characteristics significantly associated with survival in the multivariate analysis were used for the tool. Scoring points were calculated by dividing 6-month survival rates (%) by 10 and added for "],"journal":["Translational lung cancer research"],"pagination":["1433-1440"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7481607"],"repository":["biostudies-literature"],"pubmed_title":["Development of a multivariable prediction model to estimate the remaining lifespan of elderly patients with cerebral metastases from small-cell lung cancer."],"pmcid":["PMC7481607"],"pubmed_authors":["Schild SE","Rades D","Nguyen T","Janssen S"],"additional_accession":[]},"is_claimable":false,"name":"Development of a multivariable prediction model to estimate the remaining lifespan of elderly patients with cerebral metastases from small-cell lung cancer.","description":"<h4>Background</h4>Prognostic tools estimating survival of elderly patients with cerebral metastases from small-cell lung cancer (SCLC) improve treatment personalization. A specific tool for these patients was developed and compared to existing instruments.<h4>Methods</h4>One-hundred-and-forty elderly patients (≥65 years) receiving whole-brain irradiation (WBI) for cerebral metastases from SCLC were retrospectively evaluated. WBI-program, age, gender, Karnofsky performance score, number of cerebral lesions, extracerebral metastases, and interval between SCLC-diagnosis and WBI were investigated. Characteristics significantly associated with survival in the multivariate analysis were used for the tool. Scoring points were calculated by dividing 6-month survival rates (%) by 10 and added for ","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Aug","modification":"2025-04-18T22:50:21.516Z","creation":"2025-04-07T10:30:29.917Z"},"accession":"S-EPMC7481607","cross_references":{"pubmed":["32953515"],"doi":["10.21037/tlcr-20-327"]}}