biostudies-literatureUnknown20(1)Wei B<h4>Background</h4>This study aimed to evaluate whether the Homocysteine (Hcy) level was elevated in chronic obstructive pulmonary disease (COPD) patients and its correlation with the occurrence and acute progression of COPD.<h4>Methods</h4>From November 2014 to November 2015, COPD patients were enrolled from Beijing Chao-yang Hospital, and the the biological and clinical data were collected. These patients were tested in the non-acute exacerbation period and the acute exacerbation period, so they were defined as AECOPD group and Non-AECOPD group. Besides, 50 healthy subjects were recruited and defined as control group. Total plasma Hcy levels (antibodies-online, USA) were determined by enzyme-linked immunosorbent assay. Correlation analysis was used to analyze the correlation between seruBMC pulmonary medicine237https://www.ebi.ac.uk/biostudies/studies/S-EPMC7487947biostudies-literatureThe diagnostic value of homocysteine for the occurrence and acute progression of chronic obstructive pulmonary disease.PMC7487947Liu YWei BLi CTian TfalseThe diagnostic value of homocysteine for the occurrence and acute progression of chronic obstructive pulmonary disease.<h4>Background</h4>This study aimed to evaluate whether the Homocysteine (Hcy) level was elevated in chronic obstructive pulmonary disease (COPD) patients and its correlation with the occurrence and acute progression of COPD.<h4>Methods</h4>From November 2014 to November 2015, COPD patients were enrolled from Beijing Chao-yang Hospital, and the the biological and clinical data were collected. These patients were tested in the non-acute exacerbation period and the acute exacerbation period, so they were defined as AECOPD group and Non-AECOPD group. Besides, 50 healthy subjects were recruited and defined as control group. Total plasma Hcy levels (antibodies-online, USA) were determined by enzyme-linked immunosorbent assay. Correlation analysis was used to analyze the correlation between seru2020-01-01T00:00:00Z2020 Sep2025-04-05T00:29:25.517Z2020-09-19T07:01:11ZS-EPMC74879473289410810.1186/s12890-020-01265-w