{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["2020"],"submitter":["Atalar E"],"funding":["Abbott Inc"],"pubmed_abstract":["Maintaining regular blood pressure control usually requires multidrug regimens rather than monotherapy. The objective of this study was to describe the effectiveness and safety of an angiotensin-converting enzyme inhibitor and a nondihydropyridine calcium channel blocker in a single-tablet combination in patients with hypertension, a heart rate higher than 70 beats/min, and type 2 diabetes mellitus (T2DM). This study was conducted in Turkey as a prospective, noninterventional, observational study. At 22 clinical sites, the data of 200 patients with hypertension were used for efficacy analysis; however, 262 patients received at least one dose of trandolapril/verapamil fixed-dose combination at two dose strengths. Systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate, PR "],"journal":["BioMed research international"],"pagination":["2123601"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7492926"],"repository":["biostudies-literature"],"pubmed_title":["A Prospective Noninterventional, Observational Study to Describe the Effectiveness and Safety of Trandolapril and Verapamil Single-Pill Combination in the Management of Patients with Hypertension and Type 2 Diabetes Mellitus: A Harvest TR Study."],"pmcid":["PMC7492926"],"pubmed_authors":["Atalar E","Tugtekin HB","Kanyilmaz S","Karabulut A","Eskin F","Kirbiyik H","Ozyildiz AG"],"additional_accession":[]},"is_claimable":false,"name":"A Prospective Noninterventional, Observational Study to Describe the Effectiveness and Safety of Trandolapril and Verapamil Single-Pill Combination in the Management of Patients with Hypertension and Type 2 Diabetes Mellitus: A Harvest TR Study.","description":"Maintaining regular blood pressure control usually requires multidrug regimens rather than monotherapy. The objective of this study was to describe the effectiveness and safety of an angiotensin-converting enzyme inhibitor and a nondihydropyridine calcium channel blocker in a single-tablet combination in patients with hypertension, a heart rate higher than 70 beats/min, and type 2 diabetes mellitus (T2DM). This study was conducted in Turkey as a prospective, noninterventional, observational study. At 22 clinical sites, the data of 200 patients with hypertension were used for efficacy analysis; however, 262 patients received at least one dose of trandolapril/verapamil fixed-dose combination at two dose strengths. Systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate, PR ","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020","modification":"2025-04-05T07:22:35.748Z","creation":"2020-10-01T07:06:15Z"},"accession":"S-EPMC7492926","cross_references":{"pubmed":["32964020"],"doi":["10.1155/2020/2123601"]}}