biostudies-literatureShinn RLNational Cancer InstituteNCI NIH HHSAmerican College of Veterinary Internal Medicine2021-2028https://www.ebi.ac.uk/biostudies/studies/S-EPMC7517515biostudies-literatureUnknown34(5)<h4>Background</h4>Stereotactic brain biopsy (SBB) allows for histopathologic diagnosis of brain tumors. Adverse events (AE) occur in 5 to 29% of dogs after SBB, but risk factors associated with developing AE are poorly described.<h4>Objective</h4>Identify clinicopathologic, diagnostic imaging, or procedural variables that are associated with AE in dogs after SBB.<h4>Animals</h4>Twenty-nine dogs with brain tumors.<h4>Methods</h4>Retrospective, case-control study. Dogs had laboratory investigations performed before SBB, as well as clinical examinations and diagnostic imaging of the brain before and after SBB. Cases experienced AE after SBB including transient exacerbation of preexisting neurologic deficits, transient new deficits, or permanent neurologic deficits. Controls had SBB performedJournal of veterinary internal medicineRisk factors for adverse events occurring after recovery from stereotactic brain biopsy in dogs with primary intracranial neoplasia.PMC7517515R01CA139099R01CA213423P30 CA012197P01CA207206R01 CA213423P01 CA207206ACVIM Advanced Clinical Training FellowshipShinn RLHsu FCRossmeisl JHKani YfalseRisk factors for adverse events occurring after recovery from stereotactic brain biopsy in dogs with primary intracranial neoplasia.<h4>Background</h4>Stereotactic brain biopsy (SBB) allows for histopathologic diagnosis of brain tumors. Adverse events (AE) occur in 5 to 29% of dogs after SBB, but risk factors associated with developing AE are poorly described.<h4>Objective</h4>Identify clinicopathologic, diagnostic imaging, or procedural variables that are associated with AE in dogs after SBB.<h4>Animals</h4>Twenty-nine dogs with brain tumors.<h4>Methods</h4>Retrospective, case-control study. Dogs had laboratory investigations performed before SBB, as well as clinical examinations and diagnostic imaging of the brain before and after SBB. Cases experienced AE after SBB including transient exacerbation of preexisting neurologic deficits, transient new deficits, or permanent neurologic deficits. Controls had SBB performed2020-01-01T00:00:00Z2020 Sep2026-07-15T21:39:54.389Z2020-10-08T07:21:08ZS-EPMC75175153292420110.1111/jvim.15885