{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["141"],"submitter":["Lievre A"],"funding":["Leo Pharma","Bayer","ROCHE","Carthera","Transgene","Merck","Abbvie","Novartis","Biogen","Roche","Air Liquide","Lilly","Nutritheragene","Sanofi"],"pubmed_abstract":["<h4>Background</h4>Cancer patients are thought to have an increased risk of developing severe Coronavirus Disease 2019 (COVID-19) infection and of dying from the disease. In this work, predictive factors for COVID-19 severity and mortality in cancer patients were investigated.<h4>Patients and methods</h4>In this large nationwide retro-prospective cohort study, we collected data on patients with solid tumours and COVID-19 diagnosed between March 1 and 11th June 2020. The primary end-point was all-cause mortality and COVID-19 severity, defined as admission to an intensive care unit (ICU) and/or mechanical ventilation and/or death, was one of the secondary end-points.<h4>Results</h4>From April 4 to 11th June 2020, 1289 patients were analysed. The most frequent cancers were digestive and thora"],"journal":["European journal of cancer (Oxford, England : 1990)"],"pagination":["62-81"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7543792"],"repository":["biostudies-literature"],"pubmed_title":["Risk factors for Coronavirus Disease 2019 (COVID-19) severity and mortality among solid cancer patients and impact of the disease on anticancer treatment: A French nationwide cohort study (GCO-002 CACOVID-19)."],"pmcid":["PMC7543792"],"pubmed_authors":["Lacan F","Saler C","Brzyski D","Gagnaire A","Taieb J","Torche F","De Mestier L","Herve C","Chupeau P","Mahjoubi L","Gounin S","Gorphe P","Zaidi M","Babin E","Egreteau J","Sarabi M","Agnelli L","Leon V","Darloy F","Pillon D","Zabbe M","Jolimoy Boilleau G","Poulet-Potriquier S","David C","Moreira A","Prunier-Bossion F","Mansi L","Geraldo A","Andre M","Vannetzel JM","Villing AL","Barret F","Blanc JF","Bourhis J","Fadin A","Dumont P","Belmont L","Kaluzinski L","Zekri Y","Jourdaine C","Zafirova B","Goutorbe F","Ramirez C","Gschwend A","Merzoug M","Amrane K","Paoletti X","Lopez A","Caroli-Bosc FX","Lenglin E","Hugon N","Reinbolt M","Bouchaud M","Wautot V","Chauffert B","Gisselbrecht M","Di Palma F","Botsen D","Ferrand FR","Dominguez S","Meyzenc J","Gachet-Masson J","Fabre-Guillevin E","Vincent A","Laurent L","Auby D","Phelip JM","Brenet E","Belkhir K","Sarrazin F","Aparicio T","Lyamani J","Goldzak G","Nguimpi-Tambou M","Mordant P","Audemar F","Godbert B","Palmieri LJ","Baylot C","Landau A","Barlet A","Romano O","Wassermann J","Ratajczak C","Barrascout E","Saussereau M","Lerooy J","Cornet-Trichereau N","Del Piano F","Wislez M","Da Silva R","Drouillard A","Herzine H","Sibertin-Blanc C","Mavier L","Garbay D","Rebischung C","Ropert S","Charifi-Alaoui I","Mineur L","Lakkis Z","Teng W","Dos Santos E","Stroksztejn M","Valenza B","Baudin M","Agguini H","Folia M","Zaanan A","Vo M","Vozy A","Ahle G","Hardy-Bessard AC","Le Fevre C","Lafond S","Catala P","Litre CF","Rami D","Larrieu M","Gibiat S","Rivoirard R","Vergniol J","Desauw C","Bouche O","Peres C","Texereau P","Novello C","Buiret G","Regimbeau JM","Bihan C","Aziz G","Guimbaud R","Fahem R","Chagros M","Theillaumas A","Boucard C","Fontaine C","Sun XS","Gregoire C","Hee C","Mougenot E","Kanaan M","Walter T","Cloarec N","Mabro M","Langrand-Escure J","Trager Maury S","Hammad G","Dubreuil O","Esparcieux A","Sigrand J","Awad M","Dziukala C","Courtecuisse AC","Roche-Lachaise I","Thariat J","Jousset N","Lortholary A","Genin C","Lignier D","Beuvelot J","Vallard A","Bayart V","Leclercq C","Leyronnas C","Cojean-Zelek I","Le Malicot K","Kilendo D","Vignes E","Voivret F","Canellas A","Pluvy J","Duluc M","Ferrand L","Bernichon E","Eyriey M","Jacquin JP","Hennion-Imbault A","Meynard G","Evrard D","Kadiri O","Meniai F","Lenne C","Jonveaux E","Tourneur G","Cambula L","Watson S","Monard A","Di Stefano Anna L","Lam YH","Slim M","Vitellius C","Goujon G","Aldabbagh K","Naudin C","Chauvenet M","Pons I","Dujardin C","Namour C","Seitz JF","Vernisse M","Roquin G","Colomba E","Fournel P","Daemaegdt A","Bennamoun M","Collard O","Watelle F","Bertrand E","Michel O","Michel P","Mazuy C","GCO-002 CACOVID-19 collaborators/investigators","Ben Nadji H","Birr V","Guiatni A","Deshorgue AC","Noirclerc M","Leduc N","Bellecoste Martin M","Bouheret P","Saad A","Kherrour Mehdi A","Jourdan S","Vassal C","Ursu R","Kreitmann T","De Talhouet S","Dewolf M","Neuzillet C","Branco S","Vandamme H","Khamari M","Glommeau C","Lievre A","Bachet JB","Zasadny X","Moro-Sibilot D","Chablais L","Fiteni F","Le Marchand M","Gharib M","Dubois J","Billard D","Jouinot A","Leiterer C","Pernes S","Seghezzi JC","Philonenko S","Paitel JF","Panouille Q","Desgrippes R","James L","Basso M","Carola E","Durand M","Dahou S","Chive E","Lachaier E","Riviere F","Marel Lopez G","Ben Abdelghani M","Haustraete E","Chabrillac E","Belin C","Cadranel J","Genet D","Vergez S","Goulvent S","Orfeuvre H","Tisse J","Tougeron D","Mathiot 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E","Salignon K","Poureau PG","Pressoir N","Berthelot Gras C","Lancry-Lecomte L","Pripon I","Coutte A","Prome E","Lauridant G","Colle R","Dubief E","Venant-Valery M","Laurenty AP","Talfi S","Breant A","Sacco E","Prevost JB","Lucas C","Bihel V","Conroy G","Cattelain S","Graber I","Ducerf C","Laplace C","Boucheret P","Mille D","Benghadid D","Lawo M","Lebellec L","Moulin S","Pointreau Y","Fery M","Mandrou J","Philouze P","Bounouar Z","Sebbagh V","Dumazet A","Kaphan R","Bonnaire M","Bonnerave D","Roger A","GermaIn A","Vambre J","Fosse P","Richa F","Piprot C","Wagner JP","Roth G","Thoor A","Combe P","Delique L","Froura F","Naji A","Marquis E","Ducray F","Epanya C","Feuvret L","Leparree S","Poupblanc S","Saban-Roche L","Chaix M","Villeneuve E","Norguet Monnereau E","Forestier A","Locher C","Lambotin M","Perrot N","Manfredi S","Doux N","Dourthe LM","Degriffolet D","Bouras A","Mebarki S","Forestier J","Yahiaoui H","Ouahrani B","Panis V","Vazel M","Garnier Tixidre C","Houlze M","Linot 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Coronavirus Disease 2019 (COVID-19) severity and mortality among solid cancer patients and impact of the disease on anticancer treatment: A French nationwide cohort study (GCO-002 CACOVID-19).","description":"<h4>Background</h4>Cancer patients are thought to have an increased risk of developing severe Coronavirus Disease 2019 (COVID-19) infection and of dying from the disease. In this work, predictive factors for COVID-19 severity and mortality in cancer patients were investigated.<h4>Patients and methods</h4>In this large nationwide retro-prospective cohort study, we collected data on patients with solid tumours and COVID-19 diagnosed between March 1 and 11th June 2020. The primary end-point was all-cause mortality and COVID-19 severity, defined as admission to an intensive care unit (ICU) and/or mechanical ventilation and/or death, was one of the secondary end-points.<h4>Results</h4>From April 4 to 11th June 2020, 1289 patients were analysed. The most frequent cancers were digestive and thora","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Dec","modification":"2026-05-01T00:31:52.364Z","creation":"2020-10-29T09:32:03Z"},"accession":"S-EPMC7543792","cross_references":{"pubmed":["33129039"],"doi":["10.1016/j.ejca.2020.09.035"]}}