biostudies-literatureUnknown141Lievre ALeo PharmaBayerROCHECartheraTransgeneMerckAbbvieNovartisBiogenRocheAir LiquideLillyNutritherageneSanofi<h4>Background</h4>Cancer patients are thought to have an increased risk of developing severe Coronavirus Disease 2019 (COVID-19) infection and of dying from the disease. In this work, predictive factors for COVID-19 severity and mortality in cancer patients were investigated.<h4>Patients and methods</h4>In this large nationwide retro-prospective cohort study, we collected data on patients with solid tumours and COVID-19 diagnosed between March 1 and 11th June 2020. The primary end-point was all-cause mortality and COVID-19 severity, defined as admission to an intensive care unit (ICU) and/or mechanical ventilation and/or death, was one of the secondary end-points.<h4>Results</h4>From April 4 to 11th June 2020, 1289 patients were analysed. The most frequent cancers were digestive and thoraEuropean journal of cancer (Oxford, England : 1990)62-81https://www.ebi.ac.uk/biostudies/studies/S-EPMC7543792biostudies-literatureRisk factors for Coronavirus Disease 2019 (COVID-19) severity and mortality among solid cancer patients and impact of the disease on anticancer treatment: A French nationwide cohort study (GCO-002 CACOVID-19).PMC7543792Lacan FSaler CBrzyski DGagnaire ATaieb JTorche FDe Mestier LHerve CChupeau PMahjoubi LGounin SGorphe PZaidi MBabin EEgreteau JSarabi MAgnelli LLeon VDarloy FPillon DZabbe MJolimoy Boilleau GPoulet-Potriquier SDavid CMoreira APrunier-Bossion FMansi LGeraldo AAndre MVannetzel JMVilling ALBarret FBlanc JFBourhis JFadin ADumont PBelmont LKaluzinski LZekri YJourdaine CZafirova BGoutorbe FRamirez CGschwend AMerzoug MAmrane KPaoletti XLopez ACaroli-Bosc FXLenglin EHugon NReinbolt MBouchaud MWautot VChauffert BGisselbrecht MDi Palma FBotsen DFerrand FRDominguez SMeyzenc JGachet-Masson JFabre-Guillevin EVincent ALaurent LAuby DPhelip JMBrenet EBelkhir KSarrazin FAparicio TLyamani JGoldzak GNguimpi-Tambou MMordant PAudemar FGodbert BPalmieri LJBaylot CLandau ABarlet ARomano OWassermann JRatajczak CBarrascout ESaussereau MLerooy JCornet-Trichereau NDel Piano FWislez MDa Silva RDrouillard AHerzine HSibertin-Blanc CMavier LGarbay DRebischung CRopert SCharifi-Alaoui IMineur LLakkis ZTeng WDos Santos EStroksztejn MValenza BBaudin MAgguini HFolia MZaanan AVo MVozy AAhle GHardy-Bessard ACLe Fevre CLafond SCatala PLitre CFRami DLarrieu MGibiat SRivoirard RVergniol JDesauw CBouche OPeres CTexereau PNovello CBuiret GRegimbeau JMBihan CAziz GGuimbaud RFahem RChagros MTheillaumas ABoucard CFontaine CSun XSGregoire CHee CMougenot EKanaan MWalter TCloarec NMabro MLangrand-Escure JTrager Maury SHammad GDubreuil OEsparcieux ASigrand JAwad MDziukala CCourtecuisse ACRoche-Lachaise IThariat JJousset NLortholary AGenin CLignier DBeuvelot JVallard ABayart VLeclercq CLeyronnas CCojean-Zelek ILe Malicot KKilendo DVignes EVoivret FCanellas APluvy JDuluc MFerrand LBernichon EEyriey MJacquin JPHennion-Imbault AMeynard GEvrard DKadiri OMeniai FLenne CJonveaux ETourneur GCambula LWatson SMonard ADi Stefano Anna LLam YHSlim MVitellius CGoujon GAldabbagh KNaudin CChauvenet MPons IDujardin CNamour CSeitz JFVernisse MRoquin GColomba EFournel PDaemaegdt ABennamoun MCollard OWatelle FBertrand EMichel OMichel PMazuy CGCO-002 CACOVID-19 collaborators/investigatorsBen Nadji HBirr VGuiatni ADeshorgue ACNoirclerc MLeduc NBellecoste Martin MBouheret PSaad AKherrour Mehdi AJourdan SVassal CUrsu RKreitmann TDe Talhouet SDewolf MNeuzillet CBranco SVandamme HKhamari MGlommeau CLievre ABachet JBZasadny XMoro-Sibilot DChablais LFiteni FLe Marchand MGharib MDubois JBillard DJouinot ALeiterer CPernes SSeghezzi JCPhilonenko SPaitel JFPanouille QDesgrippes RJames LBasso MCarola EDurand MDahou SChive ELachaier ERiviere FMarel Lopez GBen Abdelghani MHaustraete EChabrillac EBelin CCadranel JGenet DVergez SGoulvent SOrfeuvre HTisse JTougeron DMathiot NHuysman FBalthazard AMonvoisin JCarlier CLabonne SNatur SWilliet NKlajer ELegrand SZalcman GRassoul ADjenad KSobolak NJeanson SLoutski SLuet DPigne GPeytier AWasselin JTack VFleury MDarut-Jouve ASpaeth DNlo Meyengue LMoreau LL'helgoualc'h GALacour SNouvel FSimon Anne SHouessinon ASefrioui DDehais MMarchand-Crety CMadapathage-Senanyake VBrou Marie APerrin JMeunier JRousseau DDelabarre VHautefeuille VRay-Coquard IFernandes GSoularue EPocard MLavole JJacquet EMaissiat CLaly MThirot-Bidault AOziol ELandry GGuerineau EVieillot SBieber EHamon HDebieuvre DHuet CMolin YNienguet Tsota AGuillet MBaihas DDuboisset ELatry VSuc ERamdani MIdbaih ABarriere AVassord-Dang CJany BGreletty TRaymond ETurpin AHentic Dhome OFouquet GGazeau BGuillot LLorgis VPaillaud ESalignon KPoureau PGPressoir NBerthelot Gras CLancry-Lecomte LPripon ICoutte AProme ELauridant GColle RDubief EVenant-Valery MLaurenty APTalfi SBreant ASacco EPrevost JBLucas CBihel VConroy GCattelain SGraber IDucerf CLaplace CBoucheret PMille DBenghadid DLawo MLebellec LMoulin SPointreau YFery MMandrou JPhilouze PBounouar ZSebbagh VDumazet AKaphan RBonnaire MBonnerave DRoger AGermaIn AVambre JFosse PRicha FPiprot CWagner JPRoth GThoor ACombe PDelique LFroura FNaji AMarquis EDucray FEpanya CFeuvret LLeparree SPoupblanc SSaban-Roche LChaix MVilleneuve ENorguet Monnereau EForestier ALocher CLambotin MPerrot NManfredi SDoux NDourthe LMDegriffolet DBouras AMebarki SForestier JYahiaoui HOuahrani BPanis VVazel MGarnier Tixidre CHoulze MLinot BPerruisseau-Carrier JPham-Becker AGrelet ACastanie HHuguet JBHocine FRoques BFakhry NMoquet CTouabi KMagne NPetran DOddoz JTchikladze CSpano JPLepage ILeleu OHadj Arab YDi Stefano ALRosso MBerkane RDahan LLouvet CAbdelli NTouihri Maximin LPorebski CVallee LRay Coquard IMuron TJouve JLLepage CSiembida NVeyri MGhiringhelli FCessot ACheneau CFaugeras ELatournerie MGiroux Leprieur ELeissen NRoux SPerrier HLihi RBastit VLigeza Poisson CGoasdoue HPeira FHennetier FBasson LChandirakumaran KLong JFalandry Leger CFore MVerillaud BBoone MAprelon STrouba CMirghani HMinne FMinello ANguyen VHomokos HLelu TPriou FBenrezzak NLozach-Brugirard MAyllon Ugarte JArnaud Coffin PBrouk ZAli-Mahamadou IAlmotlak HLouafi SfalseRisk factors for Coronavirus Disease 2019 (COVID-19) severity and mortality among solid cancer patients and impact of the disease on anticancer treatment: A French nationwide cohort study (GCO-002 CACOVID-19).<h4>Background</h4>Cancer patients are thought to have an increased risk of developing severe Coronavirus Disease 2019 (COVID-19) infection and of dying from the disease. In this work, predictive factors for COVID-19 severity and mortality in cancer patients were investigated.<h4>Patients and methods</h4>In this large nationwide retro-prospective cohort study, we collected data on patients with solid tumours and COVID-19 diagnosed between March 1 and 11th June 2020. The primary end-point was all-cause mortality and COVID-19 severity, defined as admission to an intensive care unit (ICU) and/or mechanical ventilation and/or death, was one of the secondary end-points.<h4>Results</h4>From April 4 to 11th June 2020, 1289 patients were analysed. The most frequent cancers were digestive and thora2020-01-01T00:00:00Z2020 Dec2026-05-01T00:31:52.364Z2020-10-29T09:32:03ZS-EPMC75437923312903910.1016/j.ejca.2020.09.035