{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Margulis K"],"funding":["Israeli Science Foundation"],"pagination":["E174"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7555055"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["10(9)"],"pubmed_abstract":["Pgr5 proteins play a major direct role in cyclic electron flow paths in plants and eukaryotic phytoplankton. The genomes of many cyanobacterial species code for Pgr5-like proteins but their function is still uncertain. Here, we present evidence that supports a link between the Synechocystis sp. PCC6803 Pgr5-like protein and the regulation of intracellular redox balance. The knockout strain, <i>pgr5</i>KO, did not display substantial phenotypic response under our experimental conditions, confirming results obtained in earlier studies. However, the overexpression strain, <i>pgr5</i>OE, accumulated 2.5-fold more chlorophyll than the wild type and displayed increased content of photosystems matching the chlorophyll increase. As a result, electron transfer rates through the photosynthetic appar"],"journal":["Life (Basel, Switzerland)"],"pubmed_title":["Over Expression of the Cyanobacterial Pgr5-Homologue Leads to Pseudoreversion in a Gene Coding for a Putative Esterase in Synechocystis 6803."],"pmcid":["PMC7555055"],"funding_grant_id":["2466/18 and 1182/19"],"pubmed_authors":["Shimakawa G","Margulis K","Krieger-Liszkay A","Murik O","Schoffman H","Zer H","Keren N","Lis H"],"additional_accession":[]},"is_claimable":false,"name":"Over Expression of the Cyanobacterial Pgr5-Homologue Leads to Pseudoreversion in a Gene Coding for a Putative Esterase in Synechocystis 6803.","description":"Pgr5 proteins play a major direct role in cyclic electron flow paths in plants and eukaryotic phytoplankton. The genomes of many cyanobacterial species code for Pgr5-like proteins but their function is still uncertain. Here, we present evidence that supports a link between the Synechocystis sp. PCC6803 Pgr5-like protein and the regulation of intracellular redox balance. The knockout strain, <i>pgr5</i>KO, did not display substantial phenotypic response under our experimental conditions, confirming results obtained in earlier studies. However, the overexpression strain, <i>pgr5</i>OE, accumulated 2.5-fold more chlorophyll than the wild type and displayed increased content of photosystems matching the chlorophyll increase. As a result, electron transfer rates through the photosynthetic appar","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Sep","modification":"2026-04-15T09:11:32.528Z","creation":"2020-10-29T10:28:53Z"},"accession":"S-EPMC7555055","cross_references":{"pubmed":["32899164"],"doi":["10.3390/life10090174"]}}