{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["59"],"submitter":["Solomou G"],"pubmed_abstract":["<h4>Background</h4>Melanotic schwannoma is a rare variant of schwannoma. Extramedullary melanotic schwannoma originates in the vicinity of nerve roots mimicking other intervertebral disc disorders. Therefore, T1 and T2-weighted MRI sequences become an essential tool for diagnosis. Aside from case reports, no large studies exist to provide consensus on the signal intensities in T1 and T2-weighted MR imaging. Moreover, no clear evidence is available to delineate prognosis. Here, a case report is presented together with a subsequent systematic review of the literature regarding this rare entity.<h4>Case description</h4>A 45-year old female presented with a one-year history of insidious onset of neck pain and paraesthesia. Magnetic resonance imaging confirmed an extramedullary lesion along the"],"journal":["Annals of medicine and surgery (2012)"],"pagination":["217-223"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7559563"],"repository":["biostudies-literature"],"pubmed_title":["Extramedullary malignant melanotic schwannoma of the spine: Case report and an up to date systematic review of the literature."],"pmcid":["PMC7559563"],"pubmed_authors":["Wong A","Pohl U","Dulanka Silva AH","Solomou G","Tzerakis N"],"additional_accession":[]},"is_claimable":false,"name":"Extramedullary malignant melanotic schwannoma of the spine: Case report and an up to date systematic review of the literature.","description":"<h4>Background</h4>Melanotic schwannoma is a rare variant of schwannoma. Extramedullary melanotic schwannoma originates in the vicinity of nerve roots mimicking other intervertebral disc disorders. Therefore, T1 and T2-weighted MRI sequences become an essential tool for diagnosis. Aside from case reports, no large studies exist to provide consensus on the signal intensities in T1 and T2-weighted MR imaging. Moreover, no clear evidence is available to delineate prognosis. Here, a case report is presented together with a subsequent systematic review of the literature regarding this rare entity.<h4>Case description</h4>A 45-year old female presented with a one-year history of insidious onset of neck pain and paraesthesia. Magnetic resonance imaging confirmed an extramedullary lesion along the","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Nov","modification":"2025-04-04T22:11:25.411Z","creation":"2020-10-29T12:32:15Z"},"accession":"S-EPMC7559563","cross_references":{"pubmed":["33088497"],"doi":["10.1016/j.amsu.2020.10.003"]}}