biostudies-literatureUnknown59Solomou G<h4>Background</h4>Melanotic schwannoma is a rare variant of schwannoma. Extramedullary melanotic schwannoma originates in the vicinity of nerve roots mimicking other intervertebral disc disorders. Therefore, T1 and T2-weighted MRI sequences become an essential tool for diagnosis. Aside from case reports, no large studies exist to provide consensus on the signal intensities in T1 and T2-weighted MR imaging. Moreover, no clear evidence is available to delineate prognosis. Here, a case report is presented together with a subsequent systematic review of the literature regarding this rare entity.<h4>Case description</h4>A 45-year old female presented with a one-year history of insidious onset of neck pain and paraesthesia. Magnetic resonance imaging confirmed an extramedullary lesion along theAnnals of medicine and surgery (2012)217-223https://www.ebi.ac.uk/biostudies/studies/S-EPMC7559563biostudies-literatureExtramedullary malignant melanotic schwannoma of the spine: Case report and an up to date systematic review of the literature.PMC7559563Wong APohl UDulanka Silva AHSolomou GTzerakis NfalseExtramedullary malignant melanotic schwannoma of the spine: Case report and an up to date systematic review of the literature.<h4>Background</h4>Melanotic schwannoma is a rare variant of schwannoma. Extramedullary melanotic schwannoma originates in the vicinity of nerve roots mimicking other intervertebral disc disorders. Therefore, T1 and T2-weighted MRI sequences become an essential tool for diagnosis. Aside from case reports, no large studies exist to provide consensus on the signal intensities in T1 and T2-weighted MR imaging. Moreover, no clear evidence is available to delineate prognosis. Here, a case report is presented together with a subsequent systematic review of the literature regarding this rare entity.<h4>Case description</h4>A 45-year old female presented with a one-year history of insidious onset of neck pain and paraesthesia. Magnetic resonance imaging confirmed an extramedullary lesion along the2020-01-01T00:00:00Z2020 Nov2025-04-04T22:11:25.411Z2020-10-29T12:32:15ZS-EPMC75595633308849710.1016/j.amsu.2020.10.003