biostudies-literatureJiang HGuangxi Forestry Research and Extension ProjectAnhui Provincial Department of EducationAnhui Key Research and Development ProgramAnhui Agricultural University Young Talent FundNational Natural Science Foundation of ChinaAnhui Provincial Postdoctoral FundThe Fundamental Research Funds for Guangxi Forestry Research InstituteEarmarked Fund for Modern Agro-industry Technology Research System in Tea Industrythe Changjiang Scholars and Innovative Research Team in UniversityE1119https://www.ebi.ac.uk/biostudies/studies/S-EPMC7569807biostudies-literatureUnknown9(9)<i>Colletotrichum gloeosporioides</i> and <i>Pseudopestalotiopsis camelliae-sinensis</i> are the two most important tea plant (<i>Camellia sinensis</i> L.) pathogenic fungi. Interest in natural plant extracts as alternatives to synthetic chemical fungicides to control plant pathogens is growing. In this study, the volatile fraction of <i>Baeckea frutescens</i> L. was extracted by supercritical fluid extraction (SFE-CO<sub>2</sub>), and its chemical composition was analyzed, and investigated for its antifungal activity against <i>C. gloeosporioides</i> and <i>P. camelliae</i>. The major constituents of the volatile fraction were β-caryophyllene (28.05%), α-caryophyllene (24.02%), δ-cadinene (6.29%) and eucalyptol (5.46%) in <i>B. frutescens</i> SFE-CO<sub>2</sub> extracts. The terpineol, liPlants (Basel, Switzerland)Chemical Composition of a Supercritical Fluid (Sfe-CO<sub>2</sub>) Extract from <i>Baeckea frutescens</i> L. Leaves and Its Bioactivity Against Two Pathogenic Fungi Isolated from the Tea Plant (<i>Camellia sinensis</i> (L.) O. Kuntze).PMC7569807202004e11020006gl2017kt19NO. CARS-19KJ20198A0196YJ2017-322017B23231902075NO. IRT1101No. 201823Qin LLiang WJiang HWang DGranato DYu FSong CZhang MfalseChemical Composition of a Supercritical Fluid (Sfe-CO<sub>2</sub>) Extract from <i>Baeckea frutescens</i> L. Leaves and Its Bioactivity Against Two Pathogenic Fungi Isolated from the Tea Plant (<i>Camellia sinensis</i> (L.) O. Kuntze).<i>Colletotrichum gloeosporioides</i> and <i>Pseudopestalotiopsis camelliae-sinensis</i> are the two most important tea plant (<i>Camellia sinensis</i> L.) pathogenic fungi. Interest in natural plant extracts as alternatives to synthetic chemical fungicides to control plant pathogens is growing. In this study, the volatile fraction of <i>Baeckea frutescens</i> L. was extracted by supercritical fluid extraction (SFE-CO<sub>2</sub>), and its chemical composition was analyzed, and investigated for its antifungal activity against <i>C. gloeosporioides</i> and <i>P. camelliae</i>. The major constituents of the volatile fraction were β-caryophyllene (28.05%), α-caryophyllene (24.02%), δ-cadinene (6.29%) and eucalyptol (5.46%) in <i>B. frutescens</i> SFE-CO<sub>2</sub> extracts. The terpineol, li2020-01-01T00:00:00Z2020 Aug2026-05-02T19:16:38.028Z2020-10-31T09:59:17ZS-EPMC75698073287253510.3390/plants9091119